Molecular basis and mechanisms of drug resistance in Mycobacterium tuberculosis: classical and new drugs

PE Almeida Da Silva… - Journal of antimicrobial …, 2011 - academic.oup.com
Tuberculosis (TB) remains one of the leading public health problems worldwide. Declared
as a global emergency in 1993 by the WHO, its control is hampered by the emergence of …

Advances in the diagnosis of tuberculosis

C Lange, T Mori - Respirology, 2010 - Wiley Online Library
Tuberculosis ranges among the leading causes of morbidity and mortality worldwide. A
diagnostic approach to a patient with possible tuberculosis includes a detailed medical …

Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis

NR Gandhi, P Nunn, K Dheda, HS Schaaf, M Zignol… - The Lancet, 2010 - thelancet.com
Although progress has been made to reduce global incidence of drug-susceptible
tuberculosis, the emergence of multidrug-resistant (MDR) and extensively drug-resistant …

Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long-term outcome, tolerability, and effect on emergence …

AH Diacon, PR Donald, A Pym… - Antimicrobial agents …, 2012 - Am Soc Microbiol
The 2-year follow-up results for a randomized placebo-controlled study of 47 patients with
multidrug-resistant pulmonary tuberculosis treated with either the new diarylquinoline …

[HTML][HTML] Worldwide emergence of extensively drug-resistant tuberculosis

NS Shah, A Wright, GH Bai, L Barrera… - Emerging infectious …, 2007 - ncbi.nlm.nih.gov
3Current affiliation: World Health Organization, Geneva, Switzerland untreatable forms of
drug-resistant TB that had not been described previously in different parts of the world, we …

Emergence of Mycobacterium tuberculosis with extensive resistance to second-line drugs--worldwide, 2000-2004.

A Wright, G Bai, L Barrera, F Boulahbal… - MMWR: Morbidity & …, 2006 - search.ebscohost.com
Assesses the emergence of extensively-drug resistant (XDR) tuberculosis (TB) worldwide
during 2000-2004. Number of XDR TB reported during the period; Implication of the …

Rapid molecular screening for multidrug-resistant tuberculosis in a high-volume public health laboratory in South Africa

M Barnard, H Albert, G Coetzee, R O'Brien… - American journal of …, 2008 - atsjournals.org
Rationale: The dual challenges to tuberculosis (TB) control of HIV infection and multidrug
resistance are particularly pressing in South Africa. Conventional methods for detecting …

Twenty years of global surveillance of antituberculosis-drug resistance

M Zignol, AS Dean, D Falzon… - … England Journal of …, 2016 - Mass Medical Soc
Twenty Years of Global Surveillance of Antituberculosis-Drug Resistance | New England Journal
of Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Extensively drug-resistant tuberculosis

M Jassal, WR Bishai - The Lancet infectious diseases, 2009 - thelancet.com
Extensively drug-resistant (XDR) tuberculosis is defined as disease caused by
Mycobacterium tuberculosis with resistance to at least isoniazid and rifampicin, any …

Mycobacterium tuberculosis Strains with Highly Discordant Rifampin Susceptibility Test Results

A Van Deun, L Barrera, I Bastian… - Journal of clinical …, 2009 - Am Soc Microbiol
The objectives of this study were to investigate the origin of highly discordant rifampin
(rifampicin)(RMP) drug susceptibility test results obtained for Mycobacterium tuberculosis …