Matrix proteoglycans: from molecular design to cellular function

RV Iozzo - Annual review of biochemistry, 1998 - annualreviews.org
The proteoglycan superfamily now contains more than 30 full-time molecules that fulfill a
variety of biological functions. Proteoglycans act as tissue organizers, influence cell growth …

Tendon: biology, biomechanics, repair, growth factors, and evolving treatment options

R James, G Kesturu, G Balian, AB Chhabra - The Journal of hand surgery, 2008 - Elsevier
Surgical treatment of tendon ruptures and lacerations is currently the most common
therapeutic modality. Tendon repair in the hand involves a slow repair process, which …

The family of the small leucine-rich proteoglycans: key regulators of matrix assembly and cellular growth

RV Iozzo - Critical reviews in biochemistry and molecular biology, 1997 - Taylor & Francis
The focus of this review is on conceptual and functional advances in our understanding of
the small leucine-rich proteoglycans. These molecules belong to an expanding gene class …

Extracorporeal shock waves promote healing of collagenase‐induced Achilles tendinitis and increase TGF‐β1 and IGF‐I expression

YJ Chen, CJ Wang, KD Yang, YR Kuo… - Journal of …, 2004 - Wiley Online Library
Extracorporeal shock waves (ESW) have recently been used in resolving tendinitis.
However, mechanisms by which ESW promote tendon repair is not fully understood. In this …

Structure and metabolism of tendons

M O'brien - Scandinavian journal of medicine & science in …, 1997 - Wiley Online Library
Structure and metabolism of tendons Page 1 Scund J Mrd Sci Sports 1997: 7: 5 5 4 1 Printed in
Denmark . All rights reserved Copjright 0 iMunksgaarrll997 Scandinavian Journal of MEDICINE …

Mechanical loading and TGF-β regulate proteoglycan synthesis in tendon

JR Robbins, SP Evanko, KG Vogel - Archives of biochemistry and …, 1997 - Elsevier
Fibrocartilage is found in tendon at sites where the tissue is subjected to transverse
compressive loadingin vivo. A significant characteristic of the tissue transition from tendon to …

Regional differences in the distribution of the proteoglycans biglycan and decorin in the extracellular matrix of atherosclerotic and restenotic human coronary arteries

R Riessen, JM Isner, E Blessing… - … American journal of …, 1994 - pmc.ncbi.nlm.nih.gov
Proteoglycans are important constituents of blood vessels and accumulate in various forms
of vascular disease. Little is known concerning the proteoglycan composition of restenotic …

Effects of transforming growth factor beta on proteoglycan synthesis by cell and explant cultures derived from the knee joint meniscus

S Collier, P Ghosh - Osteoarthritis and Cartilage, 1995 - Elsevier
Repair of meniscal tears depends in part upon the ability of the resident fibrochondrocytes to
produce new extracellular matrix molecules including proteoglycans. Three culture systems …

Platelet-derived growth factor and transforming growth factor-beta 1 differentially affect the synthesis of biglycan and decorin by monkey arterial smooth muscle cells.

E Schönherr, HT Järveläinen, MG Kinsella… - … and thrombosis: a …, 1993 - ahajournals.org
Platelet-derived growth factor (PDGF) and transforming growth factor-beta 1 (TGF-beta 1),
two growth-regulatory peptides with opposite effects on arterial smooth muscle cell (ASMC) …

Catabolism of aggrecan, decorin and biglycan in tendon

SG Rees, CR Flannery, CB Little… - Biochemical …, 2000 - portlandpress.com
We have examined the catabolism of the proteoglycans aggrecan, decorin and biglycan in
fresh tendon samples and in explant cultures of tissue from the tensional and compressed …