Hypertrophic cardiomyopathy (HCM) is the most common inherited heart disease and the
leading cause of sudden cardiac death in young people. Mutations in genes that encode …

Abstract Background Fibulin-2 (FBLN2) is a secreted extracellular matrix (ECM) glycoprotein
and has been identified in the mouse mammary gland, in cap cells of terminal end buds …

The integration of multiple omics data promises to reveal new insights into the pathogenic
mechanisms of complex human diseases, with the potential to identify avenues for the …

The EGF-containing fibulin-like extracellular matrix protein 2 (EFEMP2) is involved in
connective tissue development, elastic fiber formation, and tumor growth. In this study, we …

Myoblasts play a critical role in the regeneration of skeletal muscle following injury. It has
been reported that local elevation of transforming growth factor-β1 (TGF-β1) after skeletal …

Aims In an era of evolving diagnostic possibilities, existing diagnostic systems are not fully
sufficient to promptly recognize patients with early‐stage hypertrophic cardiomyopathy …

Background Polycystic ovary syndrome (PCOS) is a reproductive endocrine disorder. The
specific molecular mechanism of PCOS remains unclear. The aim of this study was to apply …

Background Nikaidoh translocation operation is increasingly being used for patients with
TGA, VSD and LVOTO. The early results of this operation are excellent and possibly better …

BACKGROUND: Changes in the phenotype and genotype in hypertrophic cardiomyopathy
(HCM) are thought to involve the myocardium as well as extracardiac tissues. Here, we …

Polycystic ovary syndrome (PCOS) is is associated with infertility, obesity, insulin resistance,
hyperinsulinemia, type 2 diabetes mellitus, hypertension, cardiovascular problems …