Introduction: Transdermal drug delivery has several clinical benefits over conventional
routes of drug administration. To open the transdermal route for a wider range of drugs …

Human skin acts as a primary barrier between the body and its environment. Crucial for this
skin barrier function is the lipid matrix in the outermost layer of the skin, the stratum corneum …

Although, drugs are required in the various skin compartments such as viable epidermis,
dermis, or hair follicles, to efficiently treat skin diseases, drug delivery into and across the …

The skin protects the body from unwanted influences from the environment as well as
excessive water loss. The barrier function of the skin is located in the stratum corneum (SC) …

The barrier function of the skin is primarily located in the stratum corneum (SC), the
outermost layer of the skin. The SC is composed of dead cells with highly organized lipid …

This review aims to concisely chart the development of two individual research fields,
namely nanomedicines, with specific emphasis on nanoparticles (NP) and microparticles …

A hallmark of atopic eczema (AE) is skin barrier dysfunction. Lipids in the stratum corneum
(SC), primarily ceramides, fatty acids, and cholesterol, are crucial for the barrier function, but …

Written by experienced and internationally renowned contributors, this is the fourth edition of
what has become the standard reference for cosmetic scientists and dermatologists seeking …

There is considerable interest in the skin as a site of drug application both for local and
systemic effect. However, the skin, in particular the stratum corneum, poses a formidable …

Atopic dermatitis (AD) is a chronic inflammatory skin disease in which the skin barrier
function is disrupted. In this inflammatory AD environment, cytokines are upregulated, but …