Synthesis of novel piperazine-based bis (thiazole)(1, 3, 4-thiadiazole) hybrids as anti-cancer agents through caspase-dependent apoptosis
A series of novel piperazine-based bis (thiazoles) 13a–d were synthesized in moderate to
good yields via reaction of the bis (thiosemicarbazones) 7a, b with an assortment of C-acetyl …
good yields via reaction of the bis (thiosemicarbazones) 7a, b with an assortment of C-acetyl …
Repositioning anthelmintics for the treatment of inflammatory-based pathological conditions
DCN Rodrigues, JCS Porto, IL dos Santos… - …, 2024 - Springer
Acute, uncontrolled and/or long-lasting inflammation causes a breakdown in immunological
tolerance, leading to chronicity and contributing to a series of significant local or systemic …
tolerance, leading to chronicity and contributing to a series of significant local or systemic …
A Comprehensive on Synthesis and Antimicrobial Evaluation of Substituted-Arylideneamino-5-(5-Chlorobenzofuran-2-yl)-1, 2, 4-Triazole-3-Thiol Derivatives/Schiff …
Schiff bases are well known and popular classes of organic compounds containing imine
(R2C= NH) group that are widely used as catalysts and intermediates in numerous organic …
(R2C= NH) group that are widely used as catalysts and intermediates in numerous organic …
[HTML][HTML] Synthesis, Anticancer Screening, and In Silico Evaluations of Thieno[2,3-c]pyridine Derivatives as Hsp90 Inhibitors
Background: Thieno [2, 3-c] pyridines and their analogs are not well explored for their
anticancer properties. Hence, our research aimed to establish the anticancer potential of …
anticancer properties. Hence, our research aimed to establish the anticancer potential of …
Synthesis of 4-Diazocyclohexane-Based Sulfonamide Drug scaffolds: Investigating Enzyme Inhibition, Antioxidant, and ADMET properties
A Cetin, E Oguz, EA Kazancioglu, B Güven… - Journal of Molecular …, 2025 - Elsevier
The inhibitory effects of several sulfonamide derivatives with a 4-diazocyclohexane
backbone on α-glucosidase and α-amylase enzymes were explored. IC 50 values for five …
backbone on α-glucosidase and α-amylase enzymes were explored. IC 50 values for five …
Beta Lactams Anticancer Effect on Human Breast Cancer, MCF-7 Cell Line
A Abalos - 2024 - search.proquest.com
Cancer is a disease where abnormal cells replicate uncontrollably in that same region
and/or other parts of the body. One in eight women are diagnosed with breast cancer, thus …
and/or other parts of the body. One in eight women are diagnosed with breast cancer, thus …
ANALYSIS OF THE STRUCTURE OF AMIDIC DERIVATIVES OF 3-(2-ACETYLAMIDOBENZO [D] THIAZOL-6-YL) PROPANIC ACIDS WITH MONO-N-SUBSTITUTED …
SN NOVIKOVA, EV IVANOVA, MB NIKISHINA… - ПРОБЛЕМЫ …, 2024 - elibrary.ru
Benzothiazole derivatives have a broad spectrum of pharmacological activity, in particular,
they exhibit high cytotoxicity with respect to WI-38 carcinoma cells [1], antimicrobial action …
they exhibit high cytotoxicity with respect to WI-38 carcinoma cells [1], antimicrobial action …