Cardiotoxicity following thoracic radiotherapy for lung cancer

GM Walls, C Bergom, JD Mitchell… - British Journal of …, 2024 - nature.com
Radiotherapy is the standard of care treatment for unresectable NSCLC, combined with
concurrent chemotherapy and adjuvant immunotherapy. Despite technological advances in …

Cardiac substructure delineation in radiation therapy–A state‐of‐the‐art review

RN Finnegan, A Quinn, J Booth… - Journal of Medical …, 2024 - Wiley Online Library
Delineation of cardiac substructures is crucial for a better understanding of radiation‐related
cardiotoxicities and to facilitate accurate and precise cardiac dose calculation for develo** …

Cardiac substructure radiation dose and associations with tachyarrhythmia and bradyarrhythmia after lung cancer radiotherapy

KM Atkins, SC Zhang, C Kehayias, C Guthier, J He… - Cardio Oncology, 2024 - jacc.org
Background Arrhythmias are common following radiotherapy for non–small cell lung cancer.
Objectives The aim of this study was to analyze the association of distinct arrhythmia classes …

Moving beyond mean heart dose: The importance of cardiac substructures in radiation therapy toxicity

S Bowen Jones, T Marchant… - Journal of Medical …, 2024 - Wiley Online Library
Normal tissue tolerance dose limits to the heart have been established to reduce the risk of
radiation‐induced cardiac disease (RICD). Dose constraints have been developed based …

Overview of cardiac toxicity from radiation therapy

V Chin, RN Finnegan, P Keall, J Otton… - Journal of Medical …, 2024 - Wiley Online Library
Radiotherapy is an essential part of treatment for many patients with thoracic cancers.
However, proximity of the heart to tumour targets can lead to cardiac side effects, with …

A roadmap for modelling radiation‐induced cardiac disease

SC Zhang, AP Nikolova, M Kamrava… - Journal of Medical …, 2024 - Wiley Online Library
Cardiac risk mitigation is a major priority in improving outcomes for cancer survivors as
advances in cancer screening and treatments continue to decrease cancer mortality. More …

Correction: Cardiotoxicity following thoracic radiotherapy for lung cancer

GM Walls, C Bergom, JD Mitchell… - British Journal of …, 2025 - nature.com
During the proofing process for this article, the authors requested that the rows in Table 1 be
sorted by the number present in Column A 'Author and YearL; this was overlooked by the …

Predictors of atrial fibrillation after thoracic radiotherapy

S Butler, H No, F Guo, G Merchant, NJ Park, S Jackson… - Cardio Oncology, 2024 - jacc.org
Background Atrial fibrillation (AF) has been associated with thoracic radiotherapy, but the
specific risk with irradiating different cardiac substructures remains unknown. Objectives …

Dose-volume predictors of cardiac adverse events after high-dose thoracic radiation therapy for lung cancer: a systematic review and meta-analysis

M Locquet, S Jacob, X Geets, C Beaudart - BMC cancer, 2024 - Springer
Background Lung cancer is a leading cause of cancer mortality and may require high-dose
thoracic radiation therapy (RT). However, RT significantly increases the risk of radiation …

[HTML][HTML] Association of cardiac substructure radiation dose with arrhythmia: time to move away from mean dose

G Walls, A McWilliam - Cardio Oncology, 2024 - jacc.org
Radiation therapy (RT), combined with chemotherapy and adjuvant immunotherapy,
remains the standard treatment for unresectable non–small cell lung cancer (NSCLC). 1 …