Since high-resolution structural data are still scarce, different kinds of theoretical structure
prediction algorithms are of major importance in membrane protein biochemistry. But how …

We survey computational approaches that tackle membrane protein structure and function
prediction. While describing the main ideas that have led to the development of the most …

In this study, we investigate the extent to which techniques for homology modeling that were
developed for water-soluble proteins are appropriate for membrane proteins as well. To this …

The cell wall of mycobacteria contains an unusual outer membrane of extremely low
permeability. While Escherichia coli uses more than 60 proteins to functionalize its outer …

Abstract Motivation The PRED-TMBB method is based on Hidden Markov Models and is
capable of predicting the topology of beta-barrel outer membrane proteins and discriminate …

Treponema pallidum reacts poorly with the antibodies present in rabbit and human syphilitic
sera, a property attributed to the paucity of proteins in its outer membrane. To better …

Gram-negative bacteria harness multiple protein secretion systems and secrete a large
proportion of the proteome. Proteins can be exported to periplasmic space, integrated into …

Bacterial outer membrane proteins require the beta-barrel assembly machinery (BAM) for
their correct folding and function. The central component of this machinery is BamA, an …

Motivation: Transmembrane β barrel proteins (TMBs) are found in the outer membrane of
Gram-negative bacteria, chloroplast and mitochondria. They play a major role in the …

Outer membrane proteins (OMPs) are the transmembrane proteins found in the outer
membranes of Gram-negative bacteria, mitochondria and plastids. Most prediction methods …