Coumarin–benzimidazole hybrids: A review of developments in medicinal chemistry
Coumarin and benzimidazole are privileged structures in medicinal chemistry and are
widely used in drug discovery and development due to their vast biological properties. The …
widely used in drug discovery and development due to their vast biological properties. The …
Benzimidazole-triazole hybrids as antimicrobial and antiviral agents: A systematic review
M Marinescu - Antibiotics, 2023 - mdpi.com
Bacterial infections have attracted the attention of researchers in recent decades, especially
due to the special problems they have faced, such as their increasing diversity and …
due to the special problems they have faced, such as their increasing diversity and …
New drugs are not enough-drug repositioning in oncology: An update
Drug repositioning refers to the concept of discovering novel clinical benefits of drugs that
are already known for use treating other diseases. The advantages of this are that several …
are already known for use treating other diseases. The advantages of this are that several …
The nano-based catalyst for the synthesis of benzimidazoles
The properties of benzimidazole and its derivatives have been studied over more than one
hundred years. The benzimidazole ring is an important pharmacophore in modern drug …
hundred years. The benzimidazole ring is an important pharmacophore in modern drug …
Copper-Catalyzed Construction of Benzo[4,5]imidazo[2,1-a]isoquinolines Using Calcium Carbide as a Solid Alkyne Source
H Liu, Z Li - Organic Letters, 2021 - ACS Publications
A method for the synthesis of benzo [4, 5] imidazo [2, 1-a] isoquinolines through
Sonogashira cross-coupling/nucleophilic addition tandem reactions using calcium carbide …
Sonogashira cross-coupling/nucleophilic addition tandem reactions using calcium carbide …
Antimicrobial peptides and cationic nanoparticles: a broad-spectrum weapon to fight multi-drug resistance not only in bacteria
GE Valenti, S Alfei, D Caviglia, C Domenicotti… - International journal of …, 2022 - mdpi.com
In the last few years, antibiotic resistance and, analogously, anticancer drug resistance have
increased considerably, becoming one of the main public health problems. For this reason, it …
increased considerably, becoming one of the main public health problems. For this reason, it …
Recent advances in the anticancer applications of benzimidazole derivatives
Cancer, one of the most deadly diseases worldwide, is still a crucial challenge to human
well‐being. Hence, the design and development of modern protocols to cure diverse kinds …
well‐being. Hence, the design and development of modern protocols to cure diverse kinds …
SAR investigation and optimization of benzimidazole-based derivatives as antimicrobial agents against Gram-negative bacteria
Antibiotic-resistant bacteria represent a serious threat to modern medicine and human life.
Only a minority of antibacterial agents are active against Gram-negative bacteria. Hence, the …
Only a minority of antibacterial agents are active against Gram-negative bacteria. Hence, the …
Efficient synthesis of 1, 2-disubstituted benzimidazoles catalyzed by phosphoric acid as a homogeneous catalyst under mild conditions and investigating their anti …
A green practical method for the efficient synthesis of 1-benzyl-2-phenyl-benzimidazole and
its derivatives using phosphoric acid as an eco-friendly homogeneous catalyst from the …
its derivatives using phosphoric acid as an eco-friendly homogeneous catalyst from the …
Synthesis, Antimicrobial and Antibiofilm Activities, and Molecular Docking Investigations of 2-(1H-Indol-3-yl)-1H-benzo[d]imidazole Derivatives
EY Mendogralo, LY Nesterova, ER Nasibullina… - Molecules, 2023 - mdpi.com
The treatment of many bacterial and fungal infections remains a problem due to increasing
antibiotic resistance and biofilm formation by pathogens. In the present article, a …
antibiotic resistance and biofilm formation by pathogens. In the present article, a …