Proteolytic processing of viral polyproteins is essential for retrovirus infectivity. Retroviral
proteases (PR) become activated during or after assembly of the immature, non-infectious …

Human immunodeficiency virus type 1 (HIV-1) replication is a highly regulated process
requiring the recruitment of viral and cellular components to the plasma membrane for …

The duality of liquid-liquid phase separation (LLPS) of cellular components into
membraneless organelles defines the nucleation of both normal and disease processes …

The maturation of HIV-1 viral particles is essential for viral infectivity. During maturation,
many copies of the capsid protein (CA) self-assemble into a capsid shell to enclose the viral …

The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-
associated (Cas) system discovered using bacteria has been repurposed for genome …

HIV-1 maturation occurs via multiple proteolytic cleavages of the Gag polyprotein, causing
rearrangement of the virus particle required for infectivity. Cleavage results in beta-hairpin …

Retrovirus morphogenesis entails assembly of Gag proteins and the viral genome on the
host plasma membrane, acquisition of the viral membrane and envelope proteins through …

A large number of human immunodeficiency virus 1 (HIV-1) integrase (IN) alterations,
referred to as class II substitutions, exhibit pleiotropic effects during virus replication …

The importance of develo** new vaccine technologies towards versatile platforms that can
cope with global virus outbreaks has been evidenced with the most recent severe acute …

There are many studies that model the within-host population dynamics of Human
Immunodeficiency Virus Type 1 (HIV-1) infection. However, the within-infected-cell …