Many essential cellular functions in health and disease are closely linked to the ability of
cells to respond to mechanical forces. In the context of cell adhesion to the extracellular …

Communities of epithelial cells communicate through intercellular interactions, allowing
them to coordinate their motility, which plays a key role in homeostasis, morphogenesis and …

Regulated biophysical cues, such as nanotopography, have been shown to be integral for
tissue regeneration and embryogenesis in the stem cell niche. Tissue homeostasis involves …

Contractile cells can reorganize fibrous extracellular matrices and form dense tracts of fibers
between neighboring cells. These tracts guide the development of tubular tissue structures …

A migrating cell is a molecular machine made of tens of thousands of short-lived and
interacting parts. Understanding migration means understanding the self-organization of …

There is a growing interest in the development of dynamic adaptive biomaterials for
regulation of cellular functions. However, existing materials are limited to two‐state switching …

Cells in vivo reside within complex microenvironments composed of both biochemical and
biophysical cues. The dynamic feedback between cells and their microenvironments hinges …

Cells actively sense the mechanical properties of the extracellular matrix, such as its rigidity,
morphology, and deformation. The cell–matrix interaction influences a range of cellular …

The spreading area of cells has been shown to play a central role in the determination of cell
fate and tissue morphogenesis; however, a clear understanding of how spread cell area is …

In this work, a chemomechanical model describing the growth dynamics of cell-matrix
adhesion structures (ie, focal adhesions (FAs)) is developed. We show that there are three …