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Microbioreactor systems for accelerated bioprocess development
J Hemmerich, S Noack, W Wiechert… - Biotechnology …, 2018 - Wiley Online Library
In recent years, microbioreactor (MBR) systems have evolved towards versatile bioprocess
engineering tools. They provide a unique solution to combine higher experimental …
engineering tools. They provide a unique solution to combine higher experimental …
[HTML][HTML] Short prokaryotic Argonaute systems trigger cell death upon detection of invading DNA
B Koopal, A Potocnik, SK Mutte, C Aparicio-Maldonado… - Cell, 2022 - cell.com
Argonaute proteins use single-stranded RNA or DNA guides to target complementary
nucleic acids. This allows eukaryotic Argonaute proteins to mediate RNA interference and …
nucleic acids. This allows eukaryotic Argonaute proteins to mediate RNA interference and …
General calibration of microbial growth in microplate readers
Optical density (OD) measurements of microbial growth are one of the most common
techniques used in microbiology, with applications ranging from studies of antibiotic efficacy …
techniques used in microbiology, with applications ranging from studies of antibiotic efficacy …
Robust estimation of bacterial cell count from optical density
Optical density (OD) is widely used to estimate the density of cells in liquid culture, but
cannot be compared between instruments without a standardized calibration protocol and is …
cannot be compared between instruments without a standardized calibration protocol and is …
Genomically mined acoustic reporter genes for real-time in vivo monitoring of tumors and tumor-homing bacteria
Ultrasound allows imaging at a much greater depth than optical methods, but existing
genetically encoded acoustic reporters for in vivo cellular imaging have been limited by poor …
genetically encoded acoustic reporters for in vivo cellular imaging have been limited by poor …
Measuring the burden of hundreds of BioBricks defines an evolutionary limit on constructability in synthetic biology
N Radde, GA Mortensen, D Bhat, S Shah… - Nature …, 2024 - nature.com
Engineered DNA will slow the growth of a host cell if it redirects limiting resources or
otherwise interferes with homeostasis. Escape mutants that alleviate this burden can rapidly …
otherwise interferes with homeostasis. Escape mutants that alleviate this burden can rapidly …
Effects of activated carbon on liquefaction resistance of calcareous sand treated with microbially induced calcium carbonate precipitation
Y Shan, J Zhao, H Tong, J Yuan, D Lei, Y Li - Soil Dynamics and …, 2022 - Elsevier
Microbially induced calcium carbonate precipitation (MICP) is a new, natural,
environmentally friendly treatment method for soil foundations, which can improve the …
environmentally friendly treatment method for soil foundations, which can improve the …
Droplet printing reveals the importance of micron-scale structure for bacterial ecology
Bacteria often live in diverse communities where the spatial arrangement of strains and
species is considered critical for their ecology. However, a test of this hypothesis requires …
species is considered critical for their ecology. However, a test of this hypothesis requires …
In situ characterisation and manipulation of biological systems with Chi. Bio
The precision and repeatability of in vivo biological studies is predicated upon methods for
isolating a targeted subsystem from external sources of noise and variability. However, in …
isolating a targeted subsystem from external sources of noise and variability. However, in …
Pulsatile inputs achieve tunable attenuation of gene expression variability and graded multi-gene regulation
Many natural transcription factors are regulated in a pulsatile fashion, but it remains
unknown whether synthetic gene expression systems can benefit from such dynamic …
unknown whether synthetic gene expression systems can benefit from such dynamic …