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On the origin and evolution of the dual oscillator model underlying the photoperiodic clockwork in the suprachiasmatic nucleus
Decades have now passed since Colin Pittendrigh first proposed a model of a circadian
clock composed of two coupled oscillators, individually responsive to the rising and setting …
clock composed of two coupled oscillators, individually responsive to the rising and setting …
Synaptic connectome of the Drosophila circadian clock
N Reinhard, A Fukuda, G Manoli, E Derksen… - Nature …, 2024 - nature.com
The circadian clock and its output pathways play a pivotal role in optimizing daily processes.
To obtain insights into how diverse rhythmic physiology and behaviors are orchestrated, we …
To obtain insights into how diverse rhythmic physiology and behaviors are orchestrated, we …
[HTML][HTML] Cell type-specific driver lines targeting the Drosophila central complex and their use to investigate neuropeptide expression and sleep regulation
T Wolff, M Eddison, N Chen, A Nern, P Sundaramurthi… - eLife, 2025 - elifesciences.org
The central complex (CX) plays a key role in many higher-order functions of the insect brain
including navigation and activity regulation. Genetic tools for manipulating individual cell …
including navigation and activity regulation. Genetic tools for manipulating individual cell …
Connectome-driven neural inventory of a complete visual system
Vision provides animals with detailed information about their surroundings, conveying
diverse features such as color, form, and movement across the visual scene. Computing …
diverse features such as color, form, and movement across the visual scene. Computing …
The Drosophila circadian clock circuit is a nonhierarchical network of peptidergic oscillators
SL Crespo-Flores, AF Barber - Current Opinion in Insect Science, 2022 - Elsevier
The relatively simple Drosophila circadian clock circuit consists of 150 clock neurons that
coordinate rhythmic behavior and physiology, which are generally classified based on …
coordinate rhythmic behavior and physiology, which are generally classified based on …
Neurobiology and Changing Ecosystems: Mechanisms Underlying Responses to Human-Generated Environmental Impacts
Human generated environmental change profoundly affects organisms that reside across
diverse ecosystems. Although nervous systems evolved to flexibly sense, respond, and …
diverse ecosystems. Although nervous systems evolved to flexibly sense, respond, and …
Neural connectivity molecules best identify the heterogeneous clock and dopaminergic cell types in the Drosophila adult brain
Our recent single-cell sequencing of most adult Drosophila circadian neurons indicated
notable and unexpected heterogeneity. To address whether other populations are similar …
notable and unexpected heterogeneity. To address whether other populations are similar …
Neural mechanisms of parasite-induced summiting behavior in 'zombie'Drosophila
For at least two centuries, scientists have been enthralled by the “zombie” behaviors
induced by mind-controlling parasites. Despite this interest, the mechanistic bases of these …
induced by mind-controlling parasites. Despite this interest, the mechanistic bases of these …
Overlap** central clock network circuitry regulates circadian feeding and activity rhythms in Drosophila
S Saurabh, RJ Meier, LM Pireva… - Journal of …, 2024 - journals.sagepub.com
The circadian system coordinates multiple behavioral outputs to ensure proper temporal
organization. Timing information underlying circadian regulation of behavior depends on a …
organization. Timing information underlying circadian regulation of behavior depends on a …
Characterization of clock‐related proteins and neuropeptides in Drosophila littoralis and their putative role in diapause
Insects from high latitudes spend the winter in a state of overwintering diapause, which is
characterized by arrested reproduction, reduced food intake and metabolism, and increased …
characterized by arrested reproduction, reduced food intake and metabolism, and increased …