Stem cell toxicology: a powerful tool to assess pollution effects on human health

X Yao, N Yin, F Faiola - National Science Review, 2016 - academic.oup.com
Environmental pollution is a global problem; the lack of comprehensive toxicological
assessments may lead to increased health risks. To fully understand the health effects of …

Doxorubicin triggers bioenergetic failure and p53 activation in mouse stem cell-derived cardiomyocytes

T Cunha-Oliveira, LL Ferreira, AR Coelho… - Toxicology and Applied …, 2018 - Elsevier
Doxorubicin (DOX) is a widely used anticancer drug that could be even more effective if its
clinical dosage was not limited because of delayed cardiotoxicity. Beating stem cell-derived …

Embryotoxicity of Chemotherapeutic Agents Tested Using Engineered Cardiac Organoids

M Chai - 2024 - search.proquest.com
Medication use during pregnancy presents complex considerations due to its potential for
causing congenital malformations and its implications for maternal and fetal health. With …

Modified soft elastomers for cardiac tissue engineering

C Zhu - bridges.monash.edu
Poly (glycerol sebacate)(PGS) is a biodegradable crosslinked polyester elastomer. Due to
its hemocompatibility, biodegradability, soft and flexible mechanical properties, PGS has …

Pathophysiology of Doxorubicin Cardiotoxicity: From Mitochondrial Homeostasis to Biological Clocks

LCL Ferreira - 2018 - search.proquest.com
Doxorubicin is one of the most widely used chemotherapeutic agents due to its effectiveness
against a broad-spectrum of malignancies. However, its clinical use is hampered by severe …