Nowadays, cancer is one of the deadliest diseases in the world, which has been estimated
to cause 9.9 million deaths in 2020. Conventional treatments for cancer commonly involve …

The use of medicinal plants in treating illnesses has been reported since ancestral times. In
the case of hepatic diseases, several species such as Silybum marianum, Phyllanthus niruri …

The liver is one of the most important organs in the body, performing a fundamental role in
the regulation of diverse processes, among which the metabolism, secretion, storage, and …

Silymarin, a flavonolignan from milk thistle (Silybum marianum) plant, is used for the
protection against various liver conditions in both clinical settings and experimental models …

The flavonoid silymarin extracted from the seeds of Sylibum marianum is a mixture of 6
flavolignan isomers. The 3 more important isomers are silybin (or silibinin), silydianin, and …

Background Benign prostatic hyperplasia (BPH) is a common disease in elderly men, mainly
resulted from an imbalance between cell proliferation and death. Glutathione peroxidase 3 …

Silymarin and its major constituent, Silibinin, are extracts from the medicinal plant Silybum
marianum (milk thistle) and have traditionally been used for the treatment of liver diseases …

Survivin has multiple functions including cytoprotection, inhibition of cell death, and cell‐
cycle regulation, especially at the mitotic process stage, all of which favor cancer survival …

This review focuses on the specific biological effects of optically pure silymarin flavo-
nolignans, mainly silybins A and B, isosilybins A and B, silychristins A and B, and their 2, 3 …

Introduction The increasing number of cancer patients, together with the side effects of
current chemical treatments have encouraged the exploration of the potential of Iranian …