Spatial and temporal control of chemical processes
S Aubert, M Bezagu, AC Spivey… - Nature Reviews …, 2019 - nature.com
Controlling the where and when of a chemical reaction, rather than just the if, can be an
essential component in the successful development of applications. There are a large …
essential component in the successful development of applications. There are a large …
Review of ultrasound mediated drug delivery for cancer treatment: updates from pre-clinical studies
O Couture, J Foley, NF Kassell, B Larrat… - Translational Cancer …, 2014 - tcr.amegroups.org
Therapeutic ultrasound has been used to thermally ablate solid tumors since the 90s, and a
variety of cancers are presently being treated clinically, taking advantage of ultrasound-or …
variety of cancers are presently being treated clinically, taking advantage of ultrasound-or …
Step-emulsification in a microfluidic device
We present a comprehensive study of the step-emulsification process for high-throughput
production of colloidal monodisperse droplets. The 'microfluidic step emulsifier'combines a …
production of colloidal monodisperse droplets. The 'microfluidic step emulsifier'combines a …
Nanobiotechnology-based delivery strategies: New frontiers in brain tumor targeted therapies
A Mangraviti, D Gullotti, B Tyler, H Brem - Journal of Controlled Release, 2016 - Elsevier
Despite recent technological advancements and promising preclinical experiments, brain
tumor patients are still met with limited treatment options. Some of the barriers to clinical …
tumor patients are still met with limited treatment options. Some of the barriers to clinical …
Bioorthogonal drug release from nanometric micelles in living cells
L Madegard, M Girard, BR Yaw, K Porte… - … A European Journal, 2023 - Wiley Online Library
We explored a bioorthogonal approach to release drugs from stimuli‐responsive micelles
inside tumor cells. The concept relies on sydnonimine‐based micelles that undergo …
inside tumor cells. The concept relies on sydnonimine‐based micelles that undergo …
Photoactivated in situ generation of near infrared cyanines for spatiotemporally controlled fluorescence imaging in living cells
G Song, H Heng, J Wang, R Liu, Y Huang… - Angewandte …, 2021 - Wiley Online Library
Abstract Photoactivated trimerization of 2, 3, 3‐trimethyl‐3H‐indole derivatives created near
infrared fluorophore Cy5. The synthetic method is air‐tolerant, photosensitizer free, metal …
infrared fluorophore Cy5. The synthetic method is air‐tolerant, photosensitizer free, metal …
Sequential release of nanoparticle payloads from ultrasonically burstable capsules
In many biomedical contexts ranging from chemotherapy to tissue engineering, it is
beneficial to sequentially present bioactive payloads. Explicit control over the timing and …
beneficial to sequentially present bioactive payloads. Explicit control over the timing and …
Spatially-directed cell migration in acoustically-responsive scaffolds through the controlled delivery of basic fibroblast growth factor
Hydrogels are commonly used in regenerative medicine for the delivery of growth factors
(GFs). The spatial and temporal presentations of GFs are critical for directing regenerative …
(GFs). The spatial and temporal presentations of GFs are critical for directing regenerative …
Patterning of Protein-Sequestered Liquid-Crystal Droplets Using Acoustic Wave Trap**
Development of spatially organized structures and understanding their role in controlling
kinetics of multistep chemical reactions are essential for the successful design of efficient …
kinetics of multistep chemical reactions are essential for the successful design of efficient …
Magnetoresponsive virus‐mimetic nanocapsules with dual heat‐triggered sequential‐infected multiple drug‐delivery approach for combinatorial tumor therapy
Stimuli‐responsive drug‐delivery systems constitute an appealing approach to direct and
restrict drug release spatiotemporally at the specific site of interest. However, it is difficult for …
restrict drug release spatiotemporally at the specific site of interest. However, it is difficult for …