Immediate early genes, memory and psychiatric disorders: focus on c-Fos, Egr1 and Arc
Many psychiatric disorders, despite their specific characteristics, share deficits in the
cognitive domain including executive functions, emotional control and memory. However …
cognitive domain including executive functions, emotional control and memory. However …
[HTML][HTML] Towards a comparative science of emotion: Affect and consciousness in humans and animals
The componential view of human emotion recognises that affective states comprise
conscious, behavioural, physiological, neural and cognitive elements. Although many …
conscious, behavioural, physiological, neural and cognitive elements. Although many …
Behavioral flexibility in rats and mice: contributions of distinct frontocortical regions
Research examining the contribution of genetics to behavior is increasingly focused on
higher order behavioral and cognitive processes including the ability to modify behaviors …
higher order behavioral and cognitive processes including the ability to modify behaviors …
The rodent medial prefrontal cortex and associated circuits in orchestrating adaptive behavior under variable demands
Emerging evidence implicates rodent medial prefrontal cortex (mPFC) in tasks requiring
adaptation of behavior to changing information from external and internal sources. However …
adaptation of behavior to changing information from external and internal sources. However …
Learning from the past and looking to the future: emerging perspectives for improving the treatment of psychiatric disorders
Modern neuropsychopharmacology commenced in the 1950s with the serendipitous
discovery of first-generation antipsychotics and antidepressants which were therapeutically …
discovery of first-generation antipsychotics and antidepressants which were therapeutically …
Effects of immune activation during early or late gestation on schizophrenia-related behaviour in adult rat offspring
Maternal exposure to infectious agents during gestation has been identified as a significant
risk factor for schizophrenia. Using a mouse model, past work has demonstrated that the …
risk factor for schizophrenia. Using a mouse model, past work has demonstrated that the …
Develo** treatments for cognitive deficits in schizophrenia: the challenge of translation
Schizophrenia is a life-long debilitating mental disorder affecting tens of millions of people
worldwide. The serendipitous discovery of antipsychotics focused pharmaceutical research …
worldwide. The serendipitous discovery of antipsychotics focused pharmaceutical research …
Psychosis superspectrum II: neurobiology, treatment, and implications
Alternatives to traditional categorical diagnoses have been proposed to improve the validity
and utility of psychiatric nosology. This paper continues the companion review of an …
and utility of psychiatric nosology. This paper continues the companion review of an …
Adverse effects of aromatase inhibition on the brain and behavior in a nonhuman primate
Breast cancer patients using aromatase inhibitors (AIs) as an adjuvant therapy often report
side effects, including hot flashes, mood changes, and cognitive impairment. Despite long …
side effects, including hot flashes, mood changes, and cognitive impairment. Despite long …
Experimental expansion of relative telencephalon size improves the main executive function abilities in guppy
Executive functions are a set of cognitive control processes required for optimizing goal-
directed behavior. Despite more than two centuries of research on executive functions …
directed behavior. Despite more than two centuries of research on executive functions …