BRCA1 and BRCA2 play a critical role in a variety of molecular processes related to DNA
metabolism, including homologous recombination and mediating the replication stress …

Mutations in the BRCA1 and/or BRCA2 genes (BRCAm) increase the risk of develo**
breast cancer (BC) and are found in~ 5% of unselected patients with the disease. BC …

Breast cancer is treated with a multidisciplinary approach involving surgical oncology,
radiation oncology, and medical oncology. The NCCN Clinical Practice Guidelines in …

Early breast cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆
- Annals of Oncology Skip to Main Content Advertisement Annals of Oncology European …

The 18th St Gallen International Breast Cancer Conference held in March 2023, in Vienna,
Austria, assessed significant new findings for local and systemic therapies for early breast …

Triple-negative breast cancer (TNBC) accounts for 15–20% of all breast cancers and is
characterized by an aggressive nature and a high rate of recurrence despite neoadjuvant …

Importance Germline genetic testing is recommended by practice guidelines for patients
diagnosed with cancer to enable genetically targeted treatment and identify relatives who …

Triple-negative breast cancer (TNBC) is a very heterogeneous and aggressive breast
cancer subtype with a high risk of mortality, even if diagnosed early. The mainstay of early …

Abstract The St. Gallen Consensus Conference on early breast cancer treatment 2023 was
again a live event and took place in Vienna, Austria. After 4 years and one virtual event due …

Importance Recent studies have investigated the combination of immune checkpoint
inhibitors (ICIs) with (neo) adjuvant chemotherapy in early-stage breast cancer. However …