Many traits of interest are highly heritable and genetically complex, meaning that much of
the variation they exhibit arises from differences at numerous loci in the genome. Complex …

Behavioral genetics in dogs has focused on modern breeds, which are isolated subgroups
with distinctive physical and, purportedly, behavioral characteristics. We interrogated breed …

Biobanks aim to improve our understanding of health and disease by collecting and
analysing diverse biological and phenotypic information in large samples. So far, biobanks …

Latin America continues to be severely underrepresented in genomics research, and fine-
scale genetic histories and complex trait architectures remain hidden owing to insufficient …

Mendelian randomization, a method to infer causal relationships, is confounded by genetic
correlations reflecting shared etiology. We developed a model in which a latent causal …

A fundamental goal in evolutionary biology is to understand the genetic architecture of
adaptive traits. Using whole-genome data of 3955 of Darwin's finches on the Galápagos …

A central aim of genome-wide association studies (GWASs) is to estimate direct genetic
effects: the causal effects on an individual's phenotype of the alleles that they carry …

INTRODUCTION Sex differences are widespread in humans and other mammals. For
example, the distribution of height or body size is shifted upwards in males relative to …

Behavioral genetics and cultural evolution have both revolutionized our understanding of
human behavior–largely independent of each other. Here, we reconcile these two fields …

Given the many small-effect loci uncovered by genome-wide association studies (GWAS),
polygenic scores have become central to genomic medicine, and have found application in …