Resveratrol and curcumin for Chagas disease treatment—a systematic review

CHL Imperador, CB Scarim, PL Bosquesi, JR Lopes… - Pharmaceuticals, 2022 - mdpi.com
Chagas disease (CD) is a neglected protozoan infection caused by Trypanosoma cruzi,
which affects about 7 million people worldwide. There are two available drugs in …

Pyrazoline derivatives as promising novel antischistosomal agents

CS Morais, AC Mengarda, FB Miguel, KB Enes… - Scientific Reports, 2021 - nature.com
Praziquantel is the only available drug to treat schistosomiasis, a parasitic disease that
currently infects more than 240 million people globally. Due to increasing concerns about …

Naked-eye colorimetric cyanide detection by monocarbonyl analogue of curcumin

D Matiadis, C Fountzoula, M Trapali… - Journal of Molecular …, 2022 - Elsevier
The sensing properties of a monocarbonyl analogue of curcumin (C1-MAC) for cyanide
recognition were investigated by UV-Vis absorption spectroscopy. C1-MAC was designed …

Curcumin effect on Acanthamoeba triangularis encystation under nutrient starvation

R Boonhok, S Sangkanu, S Phumjan, R Jongboonjua… - PeerJ, 2022 - peerj.com
Background Curcumin is an active compound derived from turmeric, Curcuma longa, and is
known for its benefits to human health. The amoebicidal activity of curcumin against …

Medicinal Attributes of Pyrazoline in Drug Discovery

D Arora, J Singh, S Kumar - Letters in Drug Design & Discovery, 2024 - benthamdirect.com
Pyrazoline are structurally versatile nitrogen-containing heterocycle that has gained more
attention owing to its diversified pharmacological activities. This special scaffold serves as a …

Identification of 2-(4-N, N-Dimethylaminophenyl)-5-methyl-1-phenethyl-1 H-benzimidazole targeting HIV-1 CA capsid protein and inhibiting HIV-1 replication in cellulo

G Alvarez, L van Pul, X Robert, Z Artía… - BMC Pharmacology and …, 2022 - Springer
The capsid (CA) subunit of the HIV-1 Gag polyprotein is involved in several steps of the viral
cycle, from the assembly of new viral particles to the protection of the viral genome until it …

Efeito antiparasitário do curcuminoide sintético (1E, 4E)-1, 5-BIS (4-metoxifenil) penta-1, 4-dien-3-ona sobre Trypanosoma cruzi cepa Y: mecanismos de ação e …

JW Cavalcante - 2024 - repositorio.ufc.br
Chagas Disease (CD), transmitted by T. cruzi, is considered a neglected disease and is still
a major public health problem. The main drug available for treatment is benznidazole, which …