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Proteoglycan chemical diversity drives multifunctional cell regulation and therapeutics
The extracellular matrix (ECM) constitutes a highly dynamic three-dimensional structural
network comprised of macromolecules, such as proteoglycans/glycosaminoglycans …
network comprised of macromolecules, such as proteoglycans/glycosaminoglycans …
The central role of muscle stem cells in regenerative failure with aging
Skeletal muscle mass, function, and repair capacity all progressively decline with aging,
restricting mobility, voluntary function, and quality of life. Skeletal muscle repair is facilitated …
restricting mobility, voluntary function, and quality of life. Skeletal muscle repair is facilitated …
[HTML][HTML] Duchenne muscular dystrophy: from diagnosis to therapy
Duchenne muscular dystrophy (DMD) is an X-linked inherited neuromuscular disorder due
to mutations in the dystrophin gene. It is characterized by progressive muscle weakness and …
to mutations in the dystrophin gene. It is characterized by progressive muscle weakness and …
Origins, potency, and heterogeneity of skeletal muscle fibro-adipogenic progenitors—time for new definitions
Striated muscle is a highly plastic and regenerative organ that regulates body movement,
temperature, and metabolism—all the functions needed for an individual's health and well …
temperature, and metabolism—all the functions needed for an individual's health and well …
Skeletal muscle stem cells in comfort and stress
Investigations on developmental and regenerative myogenesis have led to major advances
in decrypting stem cell properties and potential, as well as their interactions within the …
in decrypting stem cell properties and potential, as well as their interactions within the …
Striated muscle function, regeneration, and repair
As the only striated muscle tissues in the body, skeletal and cardiac muscle share numerous
structural and functional characteristics, while exhibiting vastly different size and …
structural and functional characteristics, while exhibiting vastly different size and …
Decorin as a multivalent therapeutic agent against cancer
Decorin is a prototypical small leucine-rich proteoglycan that epitomizes the multifunctional
nature of this critical gene family. Soluble decorin engages multiple receptor tyrosine …
nature of this critical gene family. Soluble decorin engages multiple receptor tyrosine …
Abnormalities in skeletal muscle myogenesis, growth, and regeneration in myotonic dystrophy
Myotonic dystrophy type 1 (DM1) and 2 (DM2) are autosomal dominant degenerative
neuromuscular disorders characterized by progressive skeletal muscle weakness, atrophy …
neuromuscular disorders characterized by progressive skeletal muscle weakness, atrophy …
Cellular dynamics of myogenic cell migration: molecular mechanisms and implications for skeletal muscle cell therapies
Directional cell migration is a critical process underlying morphogenesis and post‐natal
tissue regeneration. During embryonic myogenesis, migration of skeletal myogenic …
tissue regeneration. During embryonic myogenesis, migration of skeletal myogenic …
The effect of type 2 diabetes mellitus and obesity on muscle progenitor cell function
S Teng, P Huang - Stem cell research & therapy, 2019 - Springer
In addition to its primary function to provide movement and maintain posture, the skeletal
muscle plays important roles in energy and glucose metabolism. In healthy humans, skeletal …
muscle plays important roles in energy and glucose metabolism. In healthy humans, skeletal …