Isoxazolidine: a privileged scaffold for organic and medicinal chemistry
M Berthet, T Cheviet, G Dujardin, I Parrot… - Chemical …, 2016 - ACS Publications
The isoxazolidine ring represents one of the privileged structures in medicinal chemistry,
and there have been an increasing number of studies on isoxazolidine and isoxazolidine …
and there have been an increasing number of studies on isoxazolidine and isoxazolidine …
Asymmetric 1, 3-dipolar cycloadditions of acrylamides
M Kissane, AR Maguire - Chemical Society Reviews, 2010 - pubs.rsc.org
This critical review, which is relevant to researchers in synthetic organic chemistry, focuses
on asymmetric 1, 3-dipolar cycloadditions with acrylamides. The use of chiral acrylamides as …
on asymmetric 1, 3-dipolar cycloadditions with acrylamides. The use of chiral acrylamides as …
Synthesis, in vitro antimicrobial assessment, and computational investigation of pharmacokinetic and bioactivity properties of novel trifluoromethylated compounds …
Dipolar cycloaddition reactions of a sugar-based trifluoromethylated nitrone-to-maleimide
and allyl bromide afforded a series of cycloadducts in good yield. The same nitrone reacts …
and allyl bromide afforded a series of cycloadducts in good yield. The same nitrone reacts …
In vitro antimicrobial and α-glucosidase inhibitory potential of enantiopure cycloalkylglycine derivatives: Insights into their in silico pharmacokinetic, druglikeness, and …
The present investigation deals with the evaluation for the first time of the in vitro
antimicrobial and α-glucosidase inhibitory potential of a series of 15 enantiopure …
antimicrobial and α-glucosidase inhibitory potential of a series of 15 enantiopure …
Multifunctional isoxazolidine derivatives as α-amylase and α-glucosidase inhibitors
A Ghabi, J Brahmi, F Alminderej, S Messaoudi… - Bioorganic …, 2020 - Elsevier
A series of novel isoxazolidines based on benzaldehyde derivatives have been synthesized
from the cycloaddition of chiral menthone-based nitrone and allyl phenyl ethers. All synthetic …
from the cycloaddition of chiral menthone-based nitrone and allyl phenyl ethers. All synthetic …
Novel enantiopure isoxazolidine and C-alkyl imine oxide derivatives as potential hypoglycemic agents: Design, synthesis, dual inhibitors of α-amylase and α …
In an effort to explore a new class of antidiabetic inhibitors, a new series of isoxazolidine and
C-alkyl imine oxide derivatives scaffolds were designed, synthesized and fully …
C-alkyl imine oxide derivatives scaffolds were designed, synthesized and fully …
[HTML][HTML] Design, synthesis, molecular properties and in vitro antioxidant and antibacterial potential of novel enantiopure isoxazolidine derivatives
A novel series of enantiopure isoxazolidines have been synthesized in good yields and with
high stereoselectivity by 1, 3-dipolar cycloaddition between a (–)-menthone-derived nitrone …
high stereoselectivity by 1, 3-dipolar cycloaddition between a (–)-menthone-derived nitrone …
Stereoselective synthesis of enantiopure N-substituted pyrrolidin-2, 5-dione derivatives by 1, 3-dipolar cycloaddition and assessment of their in vitro antioxidant and …
Dipolar cycloaddition between a chiral nitrone and N-substituted maleimides afforded
unprecedented enantiopure spiro-fused heterocycles in good yields with a high enantio-and …
unprecedented enantiopure spiro-fused heterocycles in good yields with a high enantio-and …
Unprecedented stereoselective synthesis of 3-methylisoxazolidine-5-aryl-1, 2, 4-oxadiazoles via 1, 3-dipolar cycloaddition and study of their in vitro antioxidant activity
ABSTRACT The stereoselective 1, 3-dipolar cycloaddition between allyl cyanide and a
menthone-derived nitrone led to the desired isoxazolidine in good yield. Once the nitrile …
menthone-derived nitrone led to the desired isoxazolidine in good yield. Once the nitrile …
1, 3-Dipolar cycloaddition of a chiral nitrone to (E)-1, 4-dichloro-2-butene: a new efficient synthesis of (2S, 3S, 4R)-4-hydroxyisoleucine
1,3-Dipolar cycloaddition of a chiral nitrone to (E)-1,4-dichloro-2-butene: a new efficient
synthesis of (2S,3S,4R)-4-hydroxyisoleucine - ScienceDirect Skip to main contentSkip to …
synthesis of (2S,3S,4R)-4-hydroxyisoleucine - ScienceDirect Skip to main contentSkip to …