The hybridization of heterocycles presents a key opportunity to craft innovative multicyclic
compounds with enhanced biological activity. Coumarins, being broadly prevalent natural …

Infectious diseases resulting from various strains of pathogenic bacteria are among the
leading causes of death and morbidity worldwide. The currently-available antibacterial …

Since 1947, a sterically hindered phenol named 3-(tert-butyl)-4-methoxyphenol, abbreviated
here as 3-tBMP, has been widely used as a powerful preservative antioxidant for food …

Abstract 3, 4, 5-Trimethoxy-3′-hydroxy-4′-methoxystilbene (TMHMS) is an anticancer
natural stilbene that targets tubulin polymerization. According to research, oxidative stress …

Background Resveratrol (RVL) is a polyphenol-containing natural product found in a variety
of plants, including peanuts, grapes, and berry fruits. The use of RVL is linked in a great deal …

In this work, two chlorophenols with particular toxicities were transformed into their 14
corresponding coumarins (CMs). Their chemical structures were confirmed by examining the …

Fluorouracil (5-FU) has been commonly used as a chemotherapy medication in cancer
management. However, owing to its substantial side effects, limited selectivity, and tumor …

This study presents, for the first time, the synthesis of innovative conjugates identified as a
five-membered ring integrating three heteroatoms linked linearly to the coumarin framework …

A potent natural combretastatin, combretastatin A-4 (COMA4) targets the condylon active
pocket to produce anticancer effects. Studies on inflammation and oxidative stress have …

In an attempt to develop a potent, eco-friendly, and selective technique for isolating natural
coumarins, this study introduced a novel extraction technique called kinetic thermomagnetic …