Recent progress in gene therapy to deliver nucleic acids with multivalent cationic vectors
E Junquera, E Aicart - Advances in colloid and interface science, 2016 - Elsevier
Due to the potential use as transfecting agents of nucleic acids (DNA or RNA), multivalent
cationic non-viral vectors have received special attention in the last decade. Much effort has …
cationic non-viral vectors have received special attention in the last decade. Much effort has …
Stimuli-triggered structural engineering of synthetic and biological polymeric assemblies
J Zhang, X Li, X Li - Progress in polymer science, 2012 - Elsevier
Response to external stimuli is a fundamental and intrinsic behavior of living systems. There
has been increasing interest for designing and constructing responsive polymeric …
has been increasing interest for designing and constructing responsive polymeric …
Molecular spectroscopy evidence of berberine binding to DNA: comparative binding and thermodynamic profile of intercalation
XL Li, YJ Hu, H Wang, BQ Yu, HL Yue - Biomacromolecules, 2012 - ACS Publications
Berberine (BH) is an important traditional medicinal herb endowed with diverse
pharmacological and biological activities. In this work, the binding characteristics and …
pharmacological and biological activities. In this work, the binding characteristics and …
Extracellular DNA facilitates the formation of functional amyloids in Staphylococcus aureus biofilms
Persistent staphylococcal infections often involve surface‐associated communities called
biofilms. S taphylococcus aureus biofilm development is mediated by the co‐ordinated …
biofilms. S taphylococcus aureus biofilm development is mediated by the co‐ordinated …
Interaction of capsaicin with calf thymus DNA: A multi-spectroscopic and molecular modelling study
Studying the mode of interaction between small molecules and DNA has received much
attention in recent years, as many drugs have been reported to directly interact with DNA …
attention in recent years, as many drugs have been reported to directly interact with DNA …
Effects of PEGylation and Acetylation of PAMAM Dendrimers on DNA Binding, Cytotoxicity and in Vitro Transfection Efficiency
K Fant, EK Esbjörner, A Jenkins… - Molecular …, 2010 - ACS Publications
Poly (amidoamine)(PAMAM) dendrimers are promising multipotent gene delivery vectors,
providing favorable DNA condensation properties also in combination with the possibility of …
providing favorable DNA condensation properties also in combination with the possibility of …
Hyaluronic acid-coated chitosan nanoparticles: Molecular weight-dependent effects on morphology and hyaluronic acid presentation
Chitosan nanoparticles are popular carriers for the delivery of macromolecular payloads, eg
nucleic acids. In this study, nanoparticles were prepared via complexation with triphosphate …
nucleic acids. In this study, nanoparticles were prepared via complexation with triphosphate …
DNA condensation by PAMAM dendrimers: self-assembly characteristics and effect on transcription
Electrostatic shielding and steric blocking by histones are two significant factors that
participate in the control of the local rates of transcription in chromatin. As a simple model …
participate in the control of the local rates of transcription in chromatin. As a simple model …
DNA compaction by a dendrimer
At physiological pH, a PAMAM dendrimer is positively charged and can effectively bind
negatively charged DNA. Currently, there has been great interest in understanding this …
negatively charged DNA. Currently, there has been great interest in understanding this …
Complexation of siRNA with dendrimer: a molecular modeling approach
This paper reports the structural behavior and thermodynamics of the complexation of siRNA
with poly (amidoamine)(PAMAM) dendrimers of generation 3 (G3) and 4 (G4) through fully …
with poly (amidoamine)(PAMAM) dendrimers of generation 3 (G3) and 4 (G4) through fully …