Role of annexin A6 in cancer

H Qi, S Liu, C Guo, J Wang… - Oncology …, 2015‏ - spandidos-publications.com
Annexin A6 (AnxA6) is a member of a conserved superfamily of Ca2+-dependent membrane-
binding annexin proteins. It participates in membrane and cytoskeleton organization …

Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

LA Garraway, HR Widlund, MA Rubin, G Getz… - Nature, 2005‏ - nature.com
Systematic analyses of cancer genomes promise to unveil patterns of genetic alterations
linked to the genesis and spread of human cancers. High-density single-nucleotide …

Characterizing the cancer genome in lung adenocarcinoma

BA Weir, MS Woo, G Getz, S Perner, L Ding… - Nature, 2007‏ - nature.com
Somatic alterations in cellular DNA underlie almost all human cancers. The prospect of
targeted therapies and the development of high-resolution, genome-wide approaches,,,,, are …

Overexpressed oncogenic tumor-self antigens: New vaccine targets

RK Bright, JD Bright, JA Byrne - Human vaccines & …, 2014‏ - Taylor & Francis
Overexpressed tumor-self antigens represent the largest group of candidate vaccine targets.
Those exhibiting a role in oncogenesis may be some of the least studied but perhaps most …

The H19 non-coding RNA is essential for human tumor growth

IJ Matouk, N DeGroot, S Mezan, S Ayesh, R Abu-lail… - PloS one, 2007‏ - journals.plos.org
Background Mutations and epigenetic aberrant signaling of growth factors pathways
contribute to carcinogenesis. Recent studies reveal that non-coding RNAs are controllers of …

TMPRSS2:ERG Fusion-Associated Deletions Provide Insight into the Heterogeneity of Prostate Cancer

S Perner, F Demichelis, R Beroukhim… - Cancer …, 2006‏ - aacrjournals.org
Prostate cancer is a common and clinically heterogeneous disease with marked variability in
progression. The recent identification of gene fusions of the 5′-untranslated region of …

TMPRSS2-ERG fusion prostate cancer: an early molecular event associated with invasion

S Perner, JM Mosquera, F Demichelis… - The American journal …, 2007‏ - journals.lww.com
Prostate cancer (PCA) is one of the most prevalent cancers and a major leading cause of
morbidity and mortality in the Western world. The TMPRSS2-ERG fusion was recently …

Evolution of the androgen receptor pathway during progression of prostate cancer

PJM Hendriksen, NFJ Dits, K Kokame… - Cancer …, 2006‏ - aacrjournals.org
The present work focused on the potential involvement of selective adaptations of the
androgen receptor pathway in the initiation and progression of prostate cancer. We defined …

Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines

N Niu, Y Qin, BL Fridley, J Hou, KR Kalari… - Genome …, 2010‏ - genome.cshlp.org
Radiation therapy is used to treat half of all cancer patients. Response to radiation therapy
varies widely among patients. Therefore, we performed a genome-wide association study …

ETS transcription factors control transcription of EZH2 and epigenetic silencing of the tumor suppressor gene Nkx3. 1 in prostate cancer

P Kunderfranco, M Mello-Grand, R Cangemi, S Pellini… - PloS one, 2010‏ - journals.plos.org
Background ETS transcription factors regulate important signaling pathways involved in cell
differentiation and development in many tissues and have emerged as important players in …