Structure, assembly, and function of tripartite efflux and type 1 secretion systems in gram-negative bacteria

I Alav, J Kobylka, MS Kuth, KM Pos, M Picard… - Chemical …, 2021 - ACS Publications
Tripartite efflux pumps and the related type 1 secretion systems (T1SSs) in Gram-negative
organisms are diverse in function, energization, and structural organization. They form …

[HTML][HTML] The type 1 secretion pathway—the hemolysin system and beyond

S Thomas, IB Holland, L Schmitt - … et Biophysica Acta (BBA)-Molecular Cell …, 2014 - Elsevier
Type 1 secretion systems (T1SS) are wide-spread among Gram-negative bacteria. An
important example is the secretion of the hemolytic toxin HlyA from uropathogenic strains …

Driving mosquito refractoriness to Plasmodium falciparum with engineered symbiotic bacteria

S Wang, ALA Dos-Santos, W Huang, KC Liu… - Science, 2017 - science.org
The huge burden of malaria in develo** countries urgently demands the development of
novel approaches to fight this deadly disease. Although engineered symbiotic bacteria have …

Protein Secretion Systems in Pseudomonas aeruginosa: An Essay on Diversity, Evolution, and Function

A Filloux - Frontiers in microbiology, 2011 - frontiersin.org
Protein secretion systems are molecular nanomachines used by Gram-negative bacteria to
thrive within their environment. They are used to release enzymes that hydrolyze complex …

General secretion signal for the mycobacterial type VII secretion pathway

MH Daleke, R Ummels, P Bawono… - Proceedings of the …, 2012 - National Acad Sciences
Mycobacterial pathogens use specialized type VII secretion (T7S) systems to transport
crucial virulence factors across their unusual cell envelope into infected host cells. These …

Cell cycle dependent coordination of surface layer biogenesis in Caulobacter crescentus

M Herdman, B Isbilir, A von Kügelgen… - Nature …, 2024 - nature.com
Surface layers (S-layers) are proteinaceous, two-dimensional paracrystalline arrays that
constitute a major component of the cell envelope in many prokaryotic species. In this study …

[HTML][HTML] Type I secretion systems–a story of appendices

K Kanonenberg, CKW Schwarz, L Schmitt - Research in microbiology, 2013 - Elsevier
Secretion is an essential task for prokaryotic organisms to interact with their surrounding
environment. In particular, the production of extracellular proteins and peptides is important …

[HTML][HTML] Structure and mechanism of bacterial tripartite efflux pumps

A Neuberger, D Du, BF Luisi - Research in microbiology, 2018 - Elsevier
Efflux pumps are membrane proteins which contribute to multi-drug resistance. In Gram-
negative bacteria, some of these pumps form complex tripartite assemblies in association …

Structure of a type-1 secretion system ABC transporter

JLW Morgan, JF Acheson, J Zimmer - Structure, 2017 - cell.com
Summary Type-1 secretion systems (T1SSs) represent a widespread mode of protein
secretion across the cell envelope in Gram-negative bacteria. The T1SS is composed of an …

Genome sequence of Xanthomonas fuscans subsp. fuscansstrain 4834-R reveals that flagellar motility is not a general feature of xanthomonads

A Darrasse, S Carrere, V Barbe, T Boureau… - BMC genomics, 2013 - Springer
Background Xanthomonads are plant-associated bacteria responsible for diseases on
economically important crops. Xanthomonas fuscans subsp. fuscans (Xff) is one of the …