A hallmark of Alzheimer's disease (AD) are the proteinaceous aggregates formed by the
amyloid-beta peptide (Aβ) that is deposited inside the brain as amyloid plaques. The …

Zinc deficiency is commonly attributed to inadequate absorption of the metal. Instead, we
show that body zinc stores in Drosophila melanogaster depend on tryptophan consumption …

One of the effective methods for the long-term preservation of mammalian genetic resources
is the cryopreservation of semen. However, a number of parameters, including diluents, the …

Heavy metal mixtures can cause nerve damage. However, the combined effects of metal
mixtures are extremely complex and rarely studied. Zinc (Zn) homeostasis plays an integral …

Lysosome-related organelles (LROs) are a class of heterogeneous organelles conserved in
eukaryotes that primarily play a role in storage and secretion. An important function of LROs …

Zinc influx and efflux events are essential for meiotic progression in oocytes of several
mammalian and amphibian species, but it is less clear whether this evolutionary …

C. elegans numr-1/2 (nu clear-localized m etal-r esponsive) is an identical gene pair
encoding a nuclear protein previously shown to be activated by cadmium and disruption of …

Previous research using the model soil nematode Caenorhabditis elegans has revealed that
silver nanoparticles (AgNP) and their transformed counterpart, sulfidized AgNP (sAgNP) …

Progression of Alzheimer's disease is accompanied by the appearance of extracellular
deposits in the brain tissues of patients with characteristic supramolecular morphology …

Zinc is an essential nutrient—it is stored during periods of excess to promote detoxification
and released during periods of deficiency to sustain function. Lysosome-related organelles …