Microfluidic devices: a tool for nanoparticle synthesis and performance evaluation

S Gimondi, H Ferreira, RL Reis, NM Neves - ACS nano, 2023‏ - ACS Publications
The use of nanoparticles (NPs) in nanomedicine holds great promise for the treatment of
diseases for which conventional therapies present serious limitations. Additionally, NPs can …

[HTML][HTML] Uptake and transport of micro/nanoplastics in terrestrial plants: Detection, mechanisms, and influencing factors

Z Yu, X Xu, L Guo, R **, Y Lu - Science of the Total Environment, 2024‏ - Elsevier
The pervasive dispersion of micro/nanoplastics in various environmental matrices has
raised concerns regarding their potential intrusion into terrestrial ecosystems and, notably …

Effective uptake of submicrometre plastics by crop plants via a crack-entry mode

L Li, Y Luo, R Li, Q Zhou, WJGM Peijnenburg… - Nature …, 2020‏ - nature.com
Most microplastics are emitted, either directly or via the degradation of plastics, to the
terrestrial environment and accumulate in large amounts in soils, representing a potential …

Molecular dynamics simulations in drug discovery and pharmaceutical development

OMH Salo-Ahen, I Alanko, R Bhadane, AMJJ Bonvin… - Processes, 2020‏ - mdpi.com
Molecular dynamics (MD) simulations have become increasingly useful in the modern drug
development process. In this review, we give a broad overview of the current application …

[HTML][HTML] Recent progress in drug delivery

C Li, J Wang, Y Wang, H Gao, G Wei, Y Huang… - … pharmaceutica sinica B, 2019‏ - Elsevier
Drug delivery systems (DDS) are defined as methods by which drugs are delivered to
desired tissues, organs, cells and subcellular organs for drug release and absorption …

Smart and bioinspired systems for overcoming biological barriers and enhancing disease theranostics

X Li, Y Gao, H Li, JP Majoral, X Shi, A Pich - Progress in Materials Science, 2023‏ - Elsevier
Nanomedicine has emerged as a promising mean to improve theranostic efficacy and
reduce side effects. Currently, only very small percentage of injected dose reaches the solid …

A mussel-inspired film for adhesion to wet buccal tissue and efficient buccal drug delivery

S Hu, X Pei, L Duan, Z Zhu, Y Liu, J Chen… - Nature …, 2021‏ - nature.com
Administration of drugs via the buccal route has attracted much attention in recent years.
However, develo** systems with satisfactory adhesion under wet conditions and …

Liquid crystal elastomer metamaterials with giant biaxial thermal shrinkage for enhancing skin regeneration

J Wu, S Yao, H Zhang, W Man, Z Bai… - Advanced …, 2021‏ - Wiley Online Library
Liquid crystal elastomers (LCEs) are a class of soft active materials of increasing interest,
because of their excellent actuation and optical performances. While LCEs show biomimetic …

Nanoparticle elasticity affects systemic circulation lifetime by modulating adsorption of apolipoprotein AI in corona formation

M Li, X **, T Liu, F Fan, F Gao, S Chai… - Nature communications, 2022‏ - nature.com
Nanoparticle elasticity is crucial in nanoparticles' physiological fate, but how this occurs is
largely unknown. Using core-shell nanoparticles with a same PEGylated lipid bilayer shell …

Cell membrane-camouflaged nanocarriers with biomimetic deformability of erythrocytes for ultralong circulation and enhanced cancer therapy

Y Miao, Y Yang, L Guo, M Chen, X Zhou, Y Zhao… - ACS …, 2022‏ - ACS Publications
Despite considerable advancements in cell membrane-camouflaged nanocarriers to
leverage natural cell functions, artificial nanocarriers that can accurately mimic both the …