Non-invasive transcranial ultrasound stimulation for neuromodulation

G Darmani, TO Bergmann, KB Pauly, CF Caskey… - Clinical …, 2022 - Elsevier
Transcranial ultrasound stimulation (TUS) holds great potential as a tool to alter neural
circuits non-invasively in both animals and humans. In contrast to established non-invasive …

[HTML][HTML] Ultrasound neuromodulation: a review of results, mechanisms and safety

J Blackmore, S Shrivastava, J Sallet, CR Butler… - Ultrasound in medicine …, 2019 - Elsevier
Ultrasonic neuromodulation is a rapidly growing field, in which low-intensity ultrasound (US)
is delivered to nervous system tissue, resulting in transient modulation of neural activity. This …

The mechanosensitive ion channel Piezo1 contributes to ultrasound neuromodulation

J Zhu, Q **an, X Hou, KF Wong, T Zhu, Z Chen… - Proceedings of the …, 2023 - pnas.org
Transcranial low-intensity ultrasound is a promising neuromodulation modality, with the
advantages of noninvasiveness, deep penetration, and high spatiotemporal accuracy …

Focused ultrasound excites cortical neurons via mechanosensitive calcium accumulation and ion channel amplification

S Yoo, DR Mittelstein, RC Hurt, J Lacroix… - Nature …, 2022 - nature.com
Ultrasonic neuromodulation has the unique potential to provide non-invasive control of
neural activity in deep brain regions with high spatial precision and without chemical or …

Ultrasound technologies for imaging and modulating neural activity

C Rabut, S Yoo, RC Hurt, Z **, H Li, H Guo, B Ling… - Neuron, 2020 - cell.com
Visualizing and perturbing neural activity on a brain-wide scale in model animals and
humans is a major goal of neuroscience technology development. Established electrical and …

Noninvasive sub-organ ultrasound stimulation for targeted neuromodulation

V Cotero, Y Fan, T Tsaava, AM Kressel, I Hancu… - Nature …, 2019 - nature.com
Tools for noninvasively modulating neural signaling in peripheral organs will advance the
study of nerves and their effect on homeostasis and disease. Herein, we demonstrate a …

Frequency dependence of ultrasound neurostimulation in the mouse brain

PP Ye, JR Brown, KB Pauly - Ultrasound in medicine & biology, 2016 - Elsevier
Ultrasound neuromodulation holds promise as a non-invasive technique for
neuromodulation of the central nervous system. However, much remains to be determined …

Transcranial focused ultrasound (tFUS) and transcranial unfocused ultrasound (tUS) neuromodulation: from theoretical principles to stimulation practices

L Di Biase, E Falato, V Di Lazzaro - Frontiers in neurology, 2019 - frontiersin.org
Transcranial focused ultrasound is an emerging technique for non-invasive
neurostimulation. Compared to magnetic or electric non-invasive brain stimulation, this …

Focused ultrasound-mediated non-invasive brain stimulation: examination of sonication parameters

H Kim, A Chiu, SD Lee, K Fischer, SS Yoo - Brain stimulation, 2014 - Elsevier
Background Transcranial focused ultrasound (FUS) has emerged as a new brain stimulation
modality. The range of sonication parameters for successful brain stimulation warrants …

Ultrasonic neuromodulation

O Naor, S Krupa, S Shoham - Journal of neural engineering, 2016 - iopscience.iop.org
Ultrasonic waves can be non-invasively steered and focused into mm-scale regions across
the human body and brain, and their application in generating controlled artificial …