Diabetes mellitus, a chronic metabolic disorder characterized by hyperglycemia, presents a
formidable global health challenge with its associated complications. Adiponectin, an …

Metabolic syndrome (MetS) is considered a metabolic disorder that has been steadily
increasing globally and seems to parallel the increasing prevalence of obesity. It consists of …

Obesity favors the development of cardiometabolic alterations such as type 2 diabetes (T2D)
and the metabolic syndrome (MS). Obesity and the MS are distinguished by an increase in …

Mesenchymal stem cell (MSC) therapy is an emerging treatment strategy to counteract
metabolic syndromes, including obesity and its comorbid disorders. However, its …

Obesity, diabetes mellitus (mostly type 2), and COVID-19 show mutual interactions because
they are not only risk factors for both acute and chronic COVID-19 manifestations, but also …

Disturbances in adipocytokine profiles can contribute to peripheral insulin resistance and
impairment of insulin production, which are 2 primary pathophysiological mechanisms …

Obesity is a complex disease that relapses frequently and associates with multiple
complications that comprise a worldwide health priority because of its rising prevalence and …

Metabolic syndrome (MetS) is a clinical manifestation characterized by a plethora of
comorbidities, including hyperglycemia, abdominal obesity, arterial hypertension, and …

Background Excess adiposity is characterized by alterations in adipokine secretion such that
circulating leptin concentrations are increased with reductions in adiponectin. An emerging …

Obesity has a pivotal and multifaceted role in pain associated with osteoarthritis (OA),
extending beyond the mechanistic influence of BMI. It exerts its effects both directly and …