The role of muscle in insect energy homeostasis

H Bretscher, MB O'Connor - Frontiers in Physiology, 2020‏ - frontiersin.org
Maintaining energy homeostasis is critical for ensuring proper growth and maximizing
survival potential of all organisms. Here we review the role of somatic muscle in regulating …

[HTML][HTML] Balancing energy expenditure and storage with growth and biosynthesis during Drosophila development

CM Gillette, JM Tennessen, T Reis - Developmental biology, 2021‏ - Elsevier
Sustaining life requires efficient uptake of nutrients and conversion to useable forms. Almost
everything about this process is dynamic. Nutrient availability fluctuates and changing …

Untargeted metabolomics reveals the effect of selective breeding on the quality of chicken meat

K Shi, Q Zhao, M Shao, Y Duan, D Li, Y Lu, Y Tang… - Metabolites, 2022‏ - mdpi.com
The selection for improved body weight is an effective approach in animal breeding.
Guangxi Partridge chickens have differentiated into two lines under selective breeding …

Serine synthesis pathway enzyme PHGDH is critical for muscle cell biomass, anabolic metabolism, and mTORC1 signaling

S Mäntyselkä, K Kolari, P Baumert… - American Journal …, 2024‏ - journals.physiology.org
Cells use glycolytic intermediates for anabolism, eg, via the serine synthesis and pentose
phosphate pathways. However, we still understand poorly how these metabolic pathways …

Opposing effects of genetic variation in MTCH2 for obesity versus heart failure

JA Fischer, TO Monroe, LL Pesce… - Human molecular …, 2023‏ - academic.oup.com
Genetic variation in genes regulating metabolism may be advantageous in some settings
but not others. The non-failing adult heart relies heavily on fatty acids as a fuel substrate and …

TRIM32: A multifunctional protein involved in muscle homeostasis, glucose metabolism, and tumorigenesis

S Bawa, R Piccirillo, ER Geisbrecht - Biomolecules, 2021‏ - mdpi.com
Human tripartite motif family of proteins 32 (TRIM32) is a ubiquitous multifunctional protein
that has demonstrated roles in differentiation, muscle physiology and regeneration, and …

TRIM32 inhibits the proliferation and migration of pulmonary artery smooth muscle cells through the inactivation of PI3K/Akt pathway in pulmonary arterial …

Z Hu, Q Song, H Ma, Y Guo, T Zhang, H **e… - Journal of Bioenergetics …, 2021‏ - Springer
Pulmonary arterial hypertension (PAH) is a progressive and fetal cardiovascular disease.
Tripartite motif 32 (TRIM32) is a member of TRIM family that has been found to be involved …

A large-scale transgenic RNAi screen identifies transcription factors that modulate myofiber size in Drosophila

FA Graca, N Sheffield, M Puppa, D Finkelstein… - PLoS …, 2021‏ - journals.plos.org
Myofiber atrophy occurs with aging and in many diseases but the underlying mechanisms
are incompletely understood. Here, we have used> 1,100 muscle-targeted RNAi …

The seminal vesicle is a juvenile hormone-responsive tissue in adult male Drosophila melanogaster

Y Kurogi, Y Mizuno, R Hayashi, K Goyins… - Open …, 2024‏ - royalsocietypublishing.org
Juvenile hormone (JH) is one of the most essential hormones controlling insect
metamorphosis and physiology. While it is well known that JH affects many tissues …

[PDF][PDF] Comparative structural analyses of the NHL domains from the human E3 ligase TRIM–NHL family

A Chaikuad, R Zhubi, C Tredup, S Knapp - IUCrJ, 2022‏ - journals.iucr.org
Tripartite motif (TRIM) proteins constitute one of the largest subfamilies of the RING-type E3
ubiquitin ligases that play a role in diverse processes from homeostasis and immune …