Hybrid small-molecule/protein fluorescent probes are powerful tools for visualizing protein
localization and function in living cells. These hybrid probes are constructed by diverse site …

Visualizing the structure and dynamics of biomolecules is critical to understand biological
function, and requires methods to fluorescently label targets of interest in their cellular …

Inorganic metals supplement the chemical repertoire of organic molecules, especially
proteins. This requires the correct metals to associate with proteins at metalation. Protein …

The development of aggregation-induced emission enhancement (AIEE) active nanoprobes
without any synthetic complication for solution-state and organic thin-film transistor (OTFT) …

Abstract Zinc (Zn 2+) is an essential micronutrient that is required for a wide variety of
cellular processes. Tools and methods have been instrumental in revealing the myriad roles …

Zinc, which is the second most abundant trace element in the human central nervous
system, is closely associated with Alzheimer's disease (AD). However, attempts to develop …

Tools to image membrane tension in response to mechanical stimuli are badly needed in
mechanobiology. We have recently introduced mechanosensitive flipper probes to report …

Imaging proteins with high resolution is crucial for studying cellular physiology and
pathology. Fluorescence imaging is a privileged method to visualize proteins with …

The endoplasmic reticulum (ER) is the most widespread organelle within eukaryotic cells,
performing various essential functions such as protein synthesis, post-translational …

Metalation, the acquisition of metals by proteins, must avoid mis‐metalation with tighter
binding metals. This is illustrated by four selected proteins that require different metals: all …