RNA modifications have recently emerged as critical posttranscriptional regulators of gene
expression programmes. Significant advances have been made in understanding the …

N 6-methyladenosine (m 6 A) is the most abundant internal modification in mRNA that
affects RNA processing, stability, and translation. Discovered as the first RNA m 6 A …

Cancer is one of the major diseases threatening human life and health worldwide.
Epigenetic modification refers to heritable changes in the genetic material without any …

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths
worldwide. HCC has high rates of death and recurrence, as well as very low survival rates …

Hepatocellular carcinoma (HCC) is a highly mortal type of primary liver cancer. Abnormal
epigenetic modifications are present in HCC, and RNA modification is dynamic and …

Objective Fat mass and obesity-associated protein (FTO), an eraser of N 6-methyadenosine
(m6A), plays oncogenic roles in various cancers. However, its role in hepatocellular …

Abstract N6-methyladenosine (m6A) demethylase fat mass and obesity-associated gene
(FTO), previously recognized to be related with obesity and diabetes, was gradually …

In 2007, the fat mass and obesity-associated (FTO) gene was discovered initially to regulate
body mass index and obesity and was subsequently found to be the first mRNA N6 …

Background Osteosarcoma is a disease with high mortality in children and adolescents, and
metastasis is one of the important clinical features of osteosarcoma. N 6-Methyladenosine …

Liver cancer is one of the most common cancers in the world and a primary cause of cancer-
related death. In recent years, despite the great development of diagnostic methods and …