[HTML][HTML] Is Alzheimer's disease a type 3 diabetes? A critical appraisal

R Kandimalla, V Thirumala, PH Reddy - Biochimica et Biophysica Acta …, 2017 - Elsevier
Recently researchers proposed the term 'Type-3-Diabetes' for Alzheimer's disease (ad)
because of the shared molecular and cellular features among Type-1-Diabetes, Type-2 …

Intracerebroventricular streptozotocin injections as a model of Alzheimer's disease: in search of a relevant mechanism

P Grieb - Molecular neurobiology, 2016 - Springer
Abstract Streptozotocin (STZ), a glucosamine-nitrosourea compound derived from soil
bacteria and originally developed as an anticancer agent, in 1963 has been found to induce …

Type 3 diabetes is sporadic Alzheimer׳ s disease: mini-review

SM de la Monte - European neuropsychopharmacology, 2014 - Elsevier
Alzheimer׳ s disease (AD) is the most common cause of dementia in North America.
Growing evidence supports the concept that AD is a metabolic disease mediated by …

Brain metabolic dysfunction at the core of Alzheimer's disease

SM de la Monte, M Tong - Biochemical pharmacology, 2014 - Elsevier
Growing evidence supports the concept that Alzheimer's disease (AD) is fundamentally a
metabolic disease with molecular and biochemical features that correspond with diabetes …

Brain glutathione levels–a novel biomarker for mild cognitive impairment and Alzheimer's disease

PK Mandal, S Saharan, M Tripathi, G Murari - Biological psychiatry, 2015 - Elsevier
Background Extant data from in vivo animal models and postmortem studies indicate that
Alzheimer's disease (AD) pathology is associated with reduction of the brain antioxidant …

Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's disease

S M. de la Monte - Current Alzheimer Research, 2012 - benthamdirect.com
Alzheimer's disease [AD] is the most common cause of dementia in North America. Despite
30+ years of intense investigation, the field lacks consensus regarding the etiology and …

The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease

ST Ferreira, WL Klein - Neurobiology of learning and memory, 2011 - Elsevier
Alzheimer's disease (AD) is the 3rd most costly disease and the leading cause of dementia.
It can linger for many years, but ultimately is fatal, the 6th leading cause of death …

[HTML][HTML] The effects of Crocus sativus (saffron) and its constituents on nervous system: A review

MR Khazdair, MH Boskabady, M Hosseini… - Avicenna journal of …, 2015 - ncbi.nlm.nih.gov
Saffron or Crocus sativus L.(C. sativus) has been widely used as a medicinal plant to
promote human health, especially in Asia. The main components of saffron are crocin …

Nutritional and health beneficial properties of saffron (Crocus sativus L): a comprehensive review

T Abu-Izneid, A Rauf, AA Khalil… - Critical reviews in …, 2022 - Taylor & Francis
Saffron (Crocus sativus L., family Iridaceae) is used traditionally for medicinal purpose in
Chinese, Ayurvedic, Persian and Unani medicines. The bioactive constituents such as …

Alzheimer's disease: Molecular aspects and treatment opportunities using herbal drugs

S Thakral, A Yadav, V Singh, M Kumar, P Kumar… - Ageing Research …, 2023 - Elsevier
Abstract Alzheimer's disease (AD), also called senile dementia, is the most common
neurological disorder. Around 50 million people, mostly of advanced age, are suffering from …