Genomic imprinting at the mammalian Dlk1-Dio3 domain

ST da Rocha, CA Edwards, M Ito, T Ogata… - Trends in Genetics, 2008 - cell.com
Genomic imprinting causes genes to be expressed or repressed depending on their
parental origin. The majority of imprinted genes identified to date map in clusters and much …

[HTML][HTML] Possible roles of DLK1 in the Notch pathway during development and disease

FA Falix, DC Aronson, WH Lamers… - Biochimica et Biophysica …, 2012 - Elsevier
The Delta-Notch pathway is an evolutionarily conserved signaling pathway which controls a
broad range of developmental processes including cell fate determination, terminal …

Fennel (Foeniculum vulgare) seed powder increases Delta-Like Non-Canonical Notch Ligand 1 gene expression in testis, liver, and humeral muscle tissues of …

M Mohammadabadi, SH Masoudzadeh, A Khezri… - Heliyon, 2021 - cell.com
Abstract Delta-Like Non-Canonical Notch Ligand 1 (DLK1) is one of the key genes involved
in the development of muscle, liver, pancreas, and lung cells; adipocytes production; and the …

Postnatal loss of Dlk1 imprinting in stem cells and niche astrocytes regulates neurogenesis

SR Ferrón, M Charalambous, E Radford, K McEwen… - Nature, 2011 - nature.com
The gene for the atypical NOTCH ligand delta-like homologue 1 (Dlk1) encodes membrane-
bound and secreted isoforms that function in several developmental processes in vitro and …

RNAi-mediated allelic trans-interaction at the imprinted Rtl1/Peg11 locus

E Davis, F Caiment, X Tordoir, J Cavaillé… - Current Biology, 2005 - cell.com
Summary The Dlk1-Gtl2 imprinted domain, encompassing the callipyge (CLPG) locus in
sheep, has recently been shown to harbor a large number of maternally expressed miRNA …

Gene expression profiling in the early phases of DMD: a constant molecular signature characterizes DMD muscle from early postnatal life throughout disease …

M Pescatori, A Broccolini, C Minetti, E Bertini… - The FASEB …, 2007 - Wiley Online Library
Genome‐wide gene expression profiling of skeletal muscle from Duchenne muscular
dystrophy (DMD) patients has been used to describe muscle tissue alterations in DMD …

Metabolic maturation during muscle stem cell differentiation is achieved by miR-1/133a-mediated inhibition of the Dlk1-Dio3 mega gene cluster

S Wüst, S Dröse, J Heidler, I Wittig, I Klockner, A Franko… - Cell metabolism, 2018 - cell.com
Muscle stem cells undergo a dramatic metabolic switch to oxidative phosphorylation during
differentiation, which is achieved by massively increased mitochondrial activity. Since …

Epigenetics and developmental programming of welfare and production traits in farm animals

KD Sinclair, KMD Rutherford, JM Wallace… - Reproduction …, 2016 - CSIRO Publishing
The concept that postnatal health and development can be influenced by events that occur
in utero originated from epidemiological studies in humans supported by numerous …

Functions and regulatory mechanisms of lncRNAs in skeletal myogenesis, muscle disease and meat production

S Wang, J **, Z Xu, B Zuo - Cells, 2019 - mdpi.com
Myogenesis is a complex biological process, and understanding the regulatory network of
skeletal myogenesis will contribute to the treatment of human muscle related diseases and …

Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene

Y Zhou, P Cheunsuchon, Y Nakayama… - …, 2010 - journals.biologists.com
The Dlk1-Gtl2 imprinting locus is located on mouse distal chromosome 12 and consists of
multiple maternally expressed non-coding RNAs and several paternally expressed protein …