Schizophrenia—an overview

RA McCutcheon, TR Marques, OD Howes - JAMA psychiatry, 2020 - jamanetwork.com
Importance Schizophrenia is a common, severe mental illness that most clinicians will
encounter regularly during their practice. This report provides an overview of the clinical …

Schizophrenia: an integrated sociodevelopmental-cognitive model

OD Howes, RM Murray - The Lancet, 2014 - thelancet.com
Schizophrenia remains a major burden on patients and society. The dopamine hypothesis
attempts to explain the pathogenic mechanisms of the disorder, and the …

Psychosis as a transdiagnostic and extended phenotype in the general population

J Van Os, U Reininghaus - World Psychiatry, 2016 - Wiley Online Library
A large body of research indicates that weak expressions of positive psychotic symptoms
(“psychotic experiences”) can be measured in the general population, and likely represent …

Hallucinations: a systematic review of points of similarity and difference across diagnostic classes

F Waters, C Fernyhough - Schizophrenia bulletin, 2017 - academic.oup.com
Hallucinations constitute one of the 5 symptom domains of psychotic disorders in DSM-5,
suggesting diagnostic significance for that group of disorders. Although specific featural …

Risk factors for relapse following treatment for first episode psychosis: a systematic review and meta-analysis of longitudinal studies

M Alvarez-Jimenez, A Priede, SE Hetrick… - Schizophrenia …, 2012 - Elsevier
BACKGROUND: Preventing relapse is an essential element of early intervention in
psychosis, but relevant risk factors and precise relapse rates remain to be clarified. The aim …

Stress sensitivity, aberrant salience, and threat anticipation in early psychosis: an experience sampling study

U Reininghaus, MJ Kempton, L Valmaggia… - Schizophrenia …, 2016 - academic.oup.com
While contemporary models of psychosis have proposed a number of putative psychological
mechanisms, how these impact on individuals to increase intensity of psychotic experiences …

Psychological processes mediating the association between developmental trauma and specific psychotic symptoms in adults: A systematic review and meta‐analysis

MAP Bloomfield, T Chang, MJ Woodl… - World …, 2021 - Wiley Online Library
Experiencing psychological trauma during childhood and/or adolescence is associated with
an increased risk of psychosis in adulthood. However, we lack a clear knowledge of how …

Auditory verbal hallucinations in persons with and without a need for care

LC Johns, K Kompus, M Connell… - Schizophrenia …, 2014 - academic.oup.com
Auditory verbal hallucinations (AVH) are complex experiences that occur in the context of
various clinical disorders. AVH also occur in individuals from the general population who …

Childhood trauma and psychosis in a prospective cohort study: cause, effect, and directionality

I Kelleher, H Keeley, P Corcoran… - American journal of …, 2013 - psychiatryonline.org
Objective Using longitudinal and prospective measures, the authors assessed the
relationship between childhood trauma and psychotic experiences, addressing the following …

Childhood adversities and psychosis: evidence, challenges, implications

C Morgan, C Gayer‐Anderson - World psychiatry, 2016 - Wiley Online Library
There is a substantial body of research reporting evidence of associations between various
forms of childhood adversity and psychosis, across the spectrum from experiences to …