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Meiosis: dances between homologs
D Zickler, N Kleckner - Annual review of genetics, 2023 - annualreviews.org
The raison d'être of meiosis is shuffling of genetic information via Mendelian segregation
and, within individual chromosomes, by DNA crossing-over. These outcomes are enabled …
and, within individual chromosomes, by DNA crossing-over. These outcomes are enabled …
Divergence and conservation of the meiotic recombination machinery
Sexually reproducing eukaryotes use recombination between homologous chromosomes to
promote chromosome segregation during meiosis. Meiotic recombination is almost …
promote chromosome segregation during meiosis. Meiotic recombination is almost …
Meiotic recombination in mammals: localization and regulation
During meiosis, a programmed induction of DNA double-strand breaks (DSBs) leads to the
exchange of genetic material between homologous chromosomes. These exchanges …
exchange of genetic material between homologous chromosomes. These exchanges …
A brief review of vertebrate sex evolution with a pledge for integrative research: towards 'sexomics'
Triggers and biological processes controlling male or female gonadal differentiation vary in
vertebrates, with sex determination (SD) governed by environmental factors or simple to …
vertebrates, with sex determination (SD) governed by environmental factors or simple to …
[HTML][HTML] Novel insights into the genetic and epigenetic paternal contribution to the human embryo
The integrity of the sperm genome and epigenome are critical for normal embryonic
development. The advent of assisted reproductive technology has led to an increased …
development. The advent of assisted reproductive technology has led to an increased …
Interplay between synaptonemal complex, homologous recombination, and centromeres during mammalian meiosis
The intimate synapsis of homologous chromosome pairs (homologs) by synaptonemal
complexes (SCs) is an essential feature of meiosis. In many organisms, synapsis and …
complexes (SCs) is an essential feature of meiosis. In many organisms, synapsis and …
Synaptonemal complex components persist at centromeres and are required for homologous centromere pairing in mouse spermatocytes
CG Bisig, MF Guiraldelli, A Kouznetsova… - PLoS …, 2012 - journals.plos.org
Recent studies in simple model organisms have shown that centromere pairing is important
for ensuring high-fidelity meiotic chromosome segregation. However, this process and the …
for ensuring high-fidelity meiotic chromosome segregation. However, this process and the …
Multiple reorganizations of the lateral elements of the synaptonemal complex facilitate homolog segregation in Bombyx mori oocytes
Although Lepidopteran females build a synaptonemal complex (SC) in pachytene,
homologs do not crossover, necessitating an alternative method of homolog conjunction. In …
homologs do not crossover, necessitating an alternative method of homolog conjunction. In …
From equator to pole: splitting chromosomes in mitosis and meiosis
During eukaryotic cell division, chromosomes must be precisely partitioned to daughter
cells. This relies on a mechanism to move chromosomes in defined directions within the …
cells. This relies on a mechanism to move chromosomes in defined directions within the …
A new chromosome-assigned Mongolian gerbil genome allows characterization of complete centromeres and a fully heterochromatic chromosome
Chromosome-scale genome assemblies based on ultralong-read sequencing technologies
are able to illuminate previously intractable aspects of genome biology such as fine-scale …
are able to illuminate previously intractable aspects of genome biology such as fine-scale …