Different plant species within the grasses were parallel targets of domestication, giving rise
to crops with distinct evolutionary histories and traits. Key traits that distinguish these species …

An enduring question in evolutionary biology concerns the degree to which episodes of
convergent trait evolution depend on the same genetic programs, particularly over long …

Enhanced cognitive function in humans is hypothesized to result from cortical expansion
and increased cellular diversity. However, the mechanisms that drive these phenotypic …

The concept of “cell type,” though fundamental to cell biology, is controversial. Cells have
historically been classified into types based on morphology, physiology, or location. More …

Comprehensive maps of neuronal connectivity provide a foundation for understanding the
structure of neural circuits. In a circuit, neurons are diverse in morphology …

A striking paradox is that genes with conserved protein sequence, function and expression
pattern over deep time often exhibit extremely divergent cis-regulatory sequences. It remains …

Single-cell RNA sequencing is increasingly used to investigate cross-species differences
driven by gene expression and cell-type composition in plants. However, the frequent …

Finding optimal bipartite matchings—eg, matching medical students to hospitals for
residency, items to buyers in an auction, or papers to reviewers for peer review—is a …

Characterization of shared patterns of RNA expression between genes across conditions
has led to the discovery of regulatory networks and novel biological functions. However, it is …

Multicollinearity, characterized by significant co-expression patterns among genes, often
occurs in high-throughput expression data, potentially impacting the predictive model's …