Abstract The Gene Ontology (GO) knowledgebase (http://geneontology. org) is a
comprehensive resource concerning the functions of genes and gene products (proteins …

The cancer treatment landscape has changed dramatically since the turn of the century,
resulting in substantial improvements in outcomes for patients. This Review summarizes …

Abstract The Gene Ontology (GO) knowledgebase (http://geneontology. org) is a
comprehensive resource concerning the functions of genes and gene products (proteins …

The aim of the UniProt Knowledgebase (UniProtKB; https://www. uniprot. org/) is to provide
users with a comprehensive, high-quality and freely accessible set of protein sequences …

Given the global surge in autoimmune diseases, it is critical to evaluate emerging
therapeutic interventions. Despite numerous new targeted immunomodulatory therapies …

The human genome encodes approximately 20,000 proteins, many still uncharacterised. It
has become clear that scientific research tends to focus on well-studied proteins, leading to …

Abstract InterPro (https://www. ebi. ac. uk/interpro) is a freely accessible resource for the
classification of protein sequences into families. It integrates predictive models, known as …

A system for programmable export of RNA molecules from living cells would enable both
non-destructive monitoring of cell dynamics and engineering of cells capable of delivering …

Abstract We previously reported Paired-Tag, a combinatorial indexing-based method that
can simultaneously map histone modifications and gene expression at single-cell resolution …

Complex gene regulatory mechanisms underlie differentiation and reprogramming.
Contemporary single-cell lineage-tracing (scLT) methods use expressed, heritable DNA …