How microbes affect depression: underlying mechanisms via the Gut–brain axis and the modulating role of probiotics

K Suda, K Matsuda - International journal of molecular sciences, 2022 - mdpi.com
Accumulating evidence suggests that the gut microbiome influences the brain functions and
psychological state of its host via the gut–brain axis, and gut dysbiosis has been linked to …

Mood, food, and obesity

M Singh - Frontiers in psychology, 2014 - frontiersin.org
Food is a potent natural reward and food intake is a complex process. Reward and
gratification associated with food consumption leads to dopamine (DA) production, which in …

Nutritional aspects of depression

UE Lang, C Beglinger, N Schweinfurth… - Cellular Physiology and …, 2015 - karger.com
Several nutrition, food and dietary compounds have been suggested to be involved in the
onset and maintenance of depressive disorders and in the severity of depressive symptoms …

Molecular mechanisms of depression: perspectives on new treatment strategies

UE Lang, S Borgwardt - Cellular Physiology and Biochemistry, 2013 - karger.com
Depression is a multicausal disorder and has been associated with the risk to develop
cancer, dementia, diabetes, epilepsy and stroke. As a metabolic disorder depression has …

Mental health in the era of COVID-19: prevalence of psychiatric disorders in a cohort of patients with type 1 and type 2 diabetes during the social distancing

J Alessi, GB de Oliveira, DW Franco… - Diabetology & metabolic …, 2020 - Springer
Background In patients with diabetes, the prevalence of depression and anxiety symptoms is
about two to four times greater than in the general population. The association between …

Risk of completed suicide after bariatric surgery: a systematic review

C Peterhänsel, D Petroff, G Klinitzke… - Obesity …, 2013 - Wiley Online Library
Bariatric surgery is one of the most effective treatments for morbid obesity, and a large body
of research indicates significant long‐term weight loss. While overall mortality decreases in …

Ghrelin signalling and obesity: at the interface of stress, mood and food reward

H Schellekens, BC Finger, TG Dinan… - Pharmacology & …, 2012 - Elsevier
The neuronal circuitry underlying the complex relationship between stress, mood and food
intake are slowly being unravelled and several studies suggest a key role herein for the …

Examining immune-inflammatory mechanisms of probiotic supplementation in depression: secondary findings from a randomized clinical trial

L Sempach, JPK Doll, V Limbach, F Marzetta… - Translational …, 2024 - nature.com
We recently indicated that four-week probiotic supplementation significantly reduced
depression along with microbial and neural changes in people with depression. Here we …

Slow-wave activity enhancement to improve cognition

KA Wilckens, F Ferrarelli, MP Walker, DJ Buysse - Trends in neurosciences, 2018 - cell.com
Slow-wave activity (SWA), and its coupling with other sleep features, reorganizes cortical
circuitry, supporting cognition. This raises the question: can cognition be improved through …

Neurobiology of major depressive disorder

R Villanueva - Neural plasticity, 2013 - Wiley Online Library
We survey studies which relate abnormal neurogenesis to major depressive disorder.
Clinically, descriptive gene and protein expression analysis and genetic and functional …