Cancer has been a leading cause of death for decades. This dismal statistic has increased
efforts to prevent the disease or to detect it early, when treatment is less invasive, relatively …

The cyclin-dependent kinase (CDK)–RB–E2F axis forms the core transcriptional machinery
driving cell cycle progression, dictating the timing and fidelity of genome replication and …

Breast cancer is the most common cancer diagnosed in females throughout the entire world,
and it is also the primary reason why people lose their lives due to malignant tumors. The …

Mesothelioma affects mostly older individuals who have been occupationally exposed to
asbestos. The global mesothelioma incidence and mortality rates are unknown, because …

INTRODUCTION Telomeres are DNA-protein complexes located at the end of chromosomes
that protect chromosome ends from degradation and fusion. The DNA component of …

Head and neck squamous cell carcinomas (HNSCCs) arise in the mucosal linings of the
upper aerodigestive tract and are unexpectedly heterogeneous in nature. Classical risk …

From a clinical, morphological and molecular perspective, prostate cancer is a
heterogeneous disease. Primary prostate cancers are often multifocal, having …

Executive summary Food systems have the potential to nurture human health and support
environmental sustainability; however, they are currently threatening both. Providing a …

Dietary proteins are indispensable to human nutrition. In addition to their tissue-building
function, they affect body composition and regulate various metabolic pathways, as well as …

Glioblastoma (GBM) is a devastating and incurable brain tumour, with a median overall
survival of fifteen months,. Identifying the cell of origin that harbours mutations that drive …