[HTML][HTML] Peroxisome proliferator-activated receptors: A key link between lipid metabolism and cancer progression

Y Li, Y Pan, X Zhao, S Wu, F Li, Y Wang, B Liu… - Clinical Nutrition, 2024 - Elsevier
Lipids represent the essential components of membranes, serve as fuels for high-energy
processes, and play crucial roles in signaling and cellular function. One of the key hallmarks …

Taxane‐induced neurotoxicity: Pathophysiology and therapeutic perspectives

R da Costa, GF Passos, NLM Quintão… - British journal of …, 2020 - Wiley Online Library
Taxane‐derived drugs are antineoplastic agents used for the treatment of highly common
malignancies. Paclitaxel and docetaxel are the most commonly used taxanes; however …

Treating osteoarthritis pain: mechanisms of action of acetaminophen, nonsteroidal anti-inflammatory drugs, opioids, and nerve growth factor antibodies

Y D'Arcy, P Mantyh, T Yaksh, S Donevan… - Postgraduate …, 2021 - Taylor & Francis
Osteoarthritis (OA) is a common difficult-to-treat condition where the goal, in the absence of
disease-modifying treatments, is to alleviate symptoms such as pain and loss of function …

Targeting strategies for oxaliplatin-induced peripheral neuropathy: clinical syndrome, molecular basis, and drug development

Y Yang, B Zhao, X Gao, J Sun, J Ye, J Li… - Journal of experimental & …, 2021 - Springer
Oxaliplatin (OHP)-induced peripheral neurotoxicity (OIPN) is a severe clinical problem and
potentially permanent side effect of cancer treatment. For the management of OIPN, accurate …

Advances and trends of hydrogel therapy platform in localized tumor treatment: A review

B Tan, L Huang, Y Wu, J Liao - Journal of Biomedical Materials …, 2021 - Wiley Online Library
Due to limitations of treatment and the stubbornness of infiltrative tumor cells, the outcome of
conventional antitumor treatment is often compromised by a variety of factors, including …

[HTML][HTML] Chemotherapy-induced peripheral neuropathy: mechanisms and therapeutic avenues

EH Bae, MK Greenwald, AG Schwartz - Neurotherapeutics, 2021 - Elsevier
Chemotherapy-induced peripheral neuropathy (CIPN) is a serious and often persistent
adverse consequence of certain chemotherapeutic agents. It is a major dose-limiting factor …

The therapeutic potential of Nrf2 inducers in chronic pain: Evidence from preclinical studies

YQ Zhou, W Mei, XB Tian, YK Tian, DQ Liu… - Pharmacology & …, 2021 - Elsevier
Chronic pain remains an enormous health problem affecting approximatively 30% of the
world's population. Opioids as the first line analgesics often leads to undesirable side effects …

Cannabinoids, endocannabinoids, and synthetic cannabimimetic molecules in neuromuscular disorders

FA Iannotti - International Journal of Molecular Sciences, 2023 - mdpi.com
Neuromuscular disorders (NMDs) encompass a large heterogeneous group of hereditary
and acquired diseases primarily affecting motor neurons, peripheral nerves, and the skeletal …

Efficacy of essential oils in relieving cancer pain: a systematic review and meta-analysis

MT Corasaniti, G Bagetta, LA Morrone, P Tonin… - International journal of …, 2023 - mdpi.com
Over 80% of patients affected by cancer develops cancer-related pain, one of the most
feared consequences because of its intractable nature, particularly in the terminal stage of …

The role of PPARγ ligands in breast cancer: from basic research to clinical studies

G Augimeri, C Giordano, L Gelsomino, P Plastina… - Cancers, 2020 - mdpi.com
Simple Summary Breast cancer represents the most frequently diagnosed carcinoma and
the leading cause of cancer death in women. Despite advances achieved in systemic …