Juvenile myoclonic epilepsy: a system disorder of the brain

P Wolf, EMT Yacubian, G Avanzini, T Sander… - Epilepsy research, 2015 - Elsevier
The prevailing understanding of generalized epilepsy is shaped by the traditional definition
that “the responsible neuronal discharge takes place, if not throughout the entire grey matter …

Genetic generalized epilepsies in adults—challenging assumptions and dogmas

BJ Vorderwülbecke, B Wandschneider… - Nature Reviews …, 2022 - nature.com
Genetic generalized epilepsy (GGE) syndromes start during childhood or adolescence, and
four commonly persist into adulthood, making up 15–20% of all cases of epilepsy in adults …

Cognitive function in genetic generalized epilepsies: insights from neuropsychology and neuroimaging

C Ratcliffe, B Wandschneider, S Baxendale… - Frontiers in …, 2020 - frontiersin.org
Genetic generalized epilepsies (GGE), previously called idiopathic generalized epilepsies,
constitute about 20% of all epilepsies, and include childhood absence epilepsy, juvenile …

Focal abnormalities in idiopathic generalized epilepsy: a critical review of the literature

U Seneviratne, M Cook, W D'souza - Epilepsia, 2014 - Wiley Online Library
Conventionally, epilepsy is dichotomized into distinct “focal” and “generalized” categories.
However, many studies have reported so‐called focal features among patients with …

SLCO5A1 and synaptic assembly genes contribute to impulsivity in juvenile myoclonic epilepsy

D Roshandel, EJ Sanders, A Shakeshaft… - npj Genomic …, 2023 - nature.com
Elevated impulsivity is a key component of attention-deficit hyperactivity disorder (ADHD),
bipolar disorder and juvenile myoclonic epilepsy (JME). We performed a genome-wide …

Variation in prognosis and treatment outcome in juvenile myoclonic epilepsy: a Biology of Juvenile Myoclonic Epilepsy Consortium proposal for a practical definition …

G Rubboli, CP Beier, KK Selmer… - Brain …, 2023 - academic.oup.com
Reliable definitions, classifications and prognostic models are the cornerstones of stratified
medicine, but none of the current classifications systems in epilepsy address prognostic or …

Psychiatric comorbidities in pediatric epilepsy

A Dagar, T Falcone - Current psychiatry reports, 2020 - Springer
Abstract Purpose of Review Psychiatric comorbidities are close to 5-times higher in children
and youth with epilepsy (CYE) compared to general population. With epilepsy being one of …

Developmental MRI markers cosegregate juvenile patients with myoclonic epilepsy and their healthy siblings

B Wandschneider, SJ Hong, BC Bernhardt, F Fadaie… - Neurology, 2019 - neurology.org
Objective MRI studies of genetic generalized epilepsies have mainly described group-level
changes between patients and healthy controls. To determine the endophenotypic potential …

Trait impulsivity in juvenile myoclonic epilepsy

A Shakeshaft, N Panjwani, R McDowall… - Annals of clinical …, 2021 - Wiley Online Library
Objective Impulsivity is a multidimensional construct that can predispose to
psychopathology. Meta‐analysis demonstrates an association between response impulsivity …

The Iowa gambling task: A review of the historical evolution, scientific basis, and use in functional neuroimaging

S Aram, L Levy, JB Patel, AA Anderson… - Sage …, 2019 - journals.sagepub.com
The Iowa Gambling Task (IGT) provides a framework to evaluate an individual decision-
making process through a simulated card game where the risks and rewards vary by the …