[HTML][HTML] Neurofilament light and glial fibrillary acidic protein in mood and anxiety disorders: A systematic review and meta-analysis

MJY Kang, J Grewal, D Eratne, C Malpas… - Brain, behavior, and …, 2024 - Elsevier
Neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) are biomarkers of
neuronal injury measurable in cerebrospinal fluid (CSF) and blood. Despite their potential …

Elevated plasma neurofilament light and glial fibrillary acidic protein in epilepsy versus nonepileptic seizures and nonepileptic disorders

H Dobson, S Al Maawali, C Malpas, AF Santillo… - …, 2024 - Wiley Online Library
Objective Research suggests that recurrent seizures may lead to neuronal injury.
Neurofilament light chain protein (NfL) and glial fibrillary acidic protein (GFAP) levels …

Biofluid biomarkers in distinguishing young-onset dementia from primary psychiatric disorders

SM Loi, D Eratne, AF Santillo… - Current Opinion in …, 2025 - journals.lww.com
The major finding from this review was that NfL has very high sensitivity and specificity in
differentiating a range of young-onset dementias (Alzheimer's dementia, behavioural-variant …

Plasma and CSF neurofilament light chain distinguish neurodegenerative from primary psychiatric conditions in a clinical setting

D Eratne, MJY Kang, C Lewis, C Dang… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION People with neurodegenerative disorders (ND) frequently face diagnostic
delay and misdiagnosis. We investigated blood and cerebrospinal fluid (CSF) neurofilament …

Diagnostic utility of plasma ptau217, ptau181, GFAP for Alzheimer disease in a heterogeneous younger onset dementia clinical cohort

D Eratne, QX Li, C Lewis, C Dang, MJY Kang, J Grewal… - medRxiv, 2024 - medrxiv.org
Objective We investigated diagnostic utility of phosphorylated tau 217 and 181 (ptau217,
ptau181), glial fibrillary acidic protein (GFAP), amyloid beta 42 and 40 (Aβ42, Aβ40) …

Lower Circulating Gas6 Levels Are Associated with Bulbar Phenotype and Faster Disease Progression in Amyotrophic Lateral Sclerosis Patients

D Apostolo, LL Ferreira, D D'Onghia, F Vincenzi… - Molecular …, 2025 - Springer
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder that
primarily affects the motor neurons in the brain and spinal cord. While the exact cause of …

Strong diagnostic performance of plasma ptau217 for CSF biomarker-defined young-onset Alzheimer disease in a diagnostically heterogeneous clinical cohort

D Eratne, QX Li, C Lewis, C Dang, MJY Kang… - Journal of …, 2025 - Springer
Objective We investigated diagnostic utility of phosphorylated tau 217 and 181 (ptau217,
ptau181), glial fibrillary acidic protein (GFAP), amyloid beta 42 and 40 (Aβ42, Aβ40), and …

Plasma neurofilament light chain is not elevated in people with first-episode psychosis or those at ultra-high risk for psychosis

MJY Kang, D Eratne, C Wannan, AF Santillo… - Schizophrenia …, 2024 - Elsevier
Abstract Introduction Neurofilament light chain (NfL), a blood biomarker of neuronal injury,
shows promise in distinguishing neurodegenerative disorders from psychiatric conditions …

Plasma neurofilament light chain is increased in Niemann-Pick Type C but glial fibrillary acidic protein remains normal

D Eratne, C Lewis, W Kelso, S Loi, WHM Chiu… - Acta …, 2024 - cambridge.org
Objective: Niemann-Pick Type C (NPC) is a genetic neurodegenerative lysosomal storage
disorder commonly associated with psychiatric symptoms and delays to accurate diagnosis …

Plasma neurofilament light chain is elevated in Niemann-Pick Type C but glial fibrillary acidic protein is not

D Eratne, C Lewis, W Kelso, S Loi, WHM Chiu… - medRxiv, 2023 - medrxiv.org
ABSTRACT OBJECTIVE Niemann-Pick Type C (NPC) is a genetic neurodegenerative
lysosomal storage disorder commonly associated with psychiatric symptoms and delays to …