[HTML][HTML] Ferroptosis in health and disease

C Berndt, H Alborzinia, VS Amen, S Ayton, U Barayeu… - Redox biology, 2024 - Elsevier
Ferroptosis is a pervasive non-apoptotic form of cell death highly relevant in various
degenerative diseases and malignancies. The hallmark of ferroptosis is uncontrolled and …

Ascorbate peroxidase in fruits and modulation of its activity by reactive species

FJ Corpas, S González-Gordo… - Journal of Experimental …, 2024 - academic.oup.com
Ascorbate peroxidase (APX) is one of the enzymes of the ascorbate–glutathione cycle and is
the key enzyme that breaks down H2O2 with the aid of ascorbate as an electron source …

Supersulfide biology and translational medicine for disease control

U Barayeu, T Sawa, M Nishida, FY Wei… - British Journal of …, 2023 - Wiley Online Library
For decades, the major focus of redox biology has been oxygen, the most abundant element
on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial …

New aspects of redox signaling mediated by supersulfides in health and disease

T Akaike, M Morita, S Ogata, J Yoshitake… - Free Radical Biology …, 2024 - Elsevier
Oxygen molecules accept electrons from the respiratory chain in the mitochondria and are
responsible for energy production in aerobic organisms. The reactive oxygen species …

Hydrogen Sulphide: A Key Player in Plant Development and Stress Resilience

S Jaiswal, SP Singh, S Singh, R Gupta… - Plant, Cell & …, 2024 - Wiley Online Library
Based on the research conducted so far, hydrogen sulphide (H2S) plays a crucial role in the
development and stress resilience of plants. H2S, which acts as a signalling molecule …

Nitric Oxide (NO) and Hydrogen Sulfide (H2S): New Potential Biotechnological Tools for Postharvest Storage of Horticultural Crops

FJ Corpas, MA Muñoz-Vargas… - Journal of Plant Growth …, 2023 - Springer
Storage and maintenance of horticultural products in optimal conditions for a reasonable
period, once they have been harvested is a technological challenge. Diverse methods are …

[HTML][HTML] Longevity control by supersulfide-mediated mitochondrial respiration and regulation of protein quality

A Nishimura, S Yoon, T Matsunaga, T Ida, M Jung… - Redox Biology, 2024 - Elsevier
Supersulfides, which are defined as sulfur species with catenated sulfur atoms, are
increasingly being investigated in biology. We recently identified pyridoxal phosphate (PLP) …

Persulfidome of Sweet Pepper Fruits during Ripening: The Case Study of Leucine Aminopeptidase That Is Positively Modulated by H2S

MA Muñoz-Vargas, S González-Gordo, A Aroca… - Antioxidants, 2024 - mdpi.com
Protein persulfidation is a thiol-based oxidative posttranslational modification (oxiPTM) that
involves the modification of susceptible cysteine thiol groups present in peptides and …

Protein persulfidation in plants: mechanisms and functions beyond a simple stress response

A Moseler, S Wagner, AJ Meyer - Biological Chemistry, 2024 - degruyter.com
Posttranslational modifications (PTMs) can modulate the activity, localization and
interactions of proteins and (re) define their biological function. Understanding how …

[HTML][HTML] Supersulfide prevents cigarette smoke extract-induced mitochondria hyperfission and cardiomyocyte early senescence by inhibiting Drp1-filamin complex …

A Nishimura, L Zhou, Y Kato, X Mi, T Ito, Y Ibuki… - Journal of …, 2024 - Elsevier
Smoking is one of the most serious risk factors for cardiovascular diseases. Although
cigarette mainstream and sidestream smoke are significant contributors to increased …