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Cross-talk between cancer stem cells and immune cells: potential therapeutic targets in the tumor immune microenvironment
B Wu, X Shi, M Jiang, H Liu - Molecular Cancer, 2023 - Springer
Ongoing research has revealed that the existence of cancer stem cells (CSCs) is one of the
biggest obstacles in the current cancer therapy. CSCs make an influential function in tumor …
biggest obstacles in the current cancer therapy. CSCs make an influential function in tumor …
Renal cell carcinoma
Renal cell carcinoma (RCC) denotes cancer originated from the renal epithelium and
accounts for> 90% of cancers in the kidney. The disease encompasses> 10 histological and …
accounts for> 90% of cancers in the kidney. The disease encompasses> 10 histological and …
New therapies for advanced thyroid cancer
Thyroid cancer is the most common endocrine cancer. The discovery of new biomarkers for
thyroid cancer has significantly improved the understanding of the molecular pathogenesis …
thyroid cancer has significantly improved the understanding of the molecular pathogenesis …
Immunotherapy for colorectal cancer: rational strategies and novel therapeutic progress
There are increasing incidences and mortality rates for colorectal cancer in the world. It is
common for chemotherapy and radiation given to patients with colorectal cancer to cause …
common for chemotherapy and radiation given to patients with colorectal cancer to cause …
Soluble PD-1 and PD-L1: predictive and prognostic significance in cancer
X Zhu, J Lang - Oncotarget, 2017 - pmc.ncbi.nlm.nih.gov
The membrane-bound molecules programmed death 1 (PD-1) and its ligand PD-L1 (PD-
1/PD-L1) belong to the immune checkpoint pathway. PD-1 pathway downregulates effector …
1/PD-L1) belong to the immune checkpoint pathway. PD-1 pathway downregulates effector …
PD-1 and its ligands are important immune checkpoints in cancer
Y Dong, Q Sun, X Zhang - Oncotarget, 2016 - pmc.ncbi.nlm.nih.gov
Checkpoint programmed death-1 (PD-1)/programmed cell death ligands (PD-Ls) have been
identified as negative immunoregulatory molecules that promote immune evasion of tumor …
identified as negative immunoregulatory molecules that promote immune evasion of tumor …
Genomic analysis of immune cell infiltrates across 11 tumor types
Background: Immune infiltration of the tumor microenvironment has been associated with
improved survival for some patients with solid tumors. The precise makeup and prognostic …
improved survival for some patients with solid tumors. The precise makeup and prognostic …
Self-delivery photo-immune stimulators for photodynamic sensitized tumor immunotherapy
Self-delivery of photosensitizer and immune modulator to tumor site is highly
recommendable to improve the photodynamic immunotherapy yet remains challenging …
recommendable to improve the photodynamic immunotherapy yet remains challenging …
Diverse types of dermatologic toxicities from immune checkpoint blockade therapy
Immunomodulatory drugs that leverages host immune mechanisms to destroy tumor cells
have been met with great promise in the treatment of cancer. Immunotherapy, targeting …
have been met with great promise in the treatment of cancer. Immunotherapy, targeting …
Peritumoural neutrophils negatively regulate adaptive immunity via the PD-L1/PD-1 signalling pathway in hepatocellular carcinoma
G He, H Zhang, J Zhou, B Wang, Y Chen… - Journal of Experimental …, 2015 - Springer
Background PD-L1 expression on neutrophils contributes to the impaired immune response
in infectious disease, but the detailed role of PD-L1 expression on neutrophils in HCC …
in infectious disease, but the detailed role of PD-L1 expression on neutrophils in HCC …