Coffee is one of the most widely consumed beverages worldwide, and epidemiology studies
associate higher coffee consumption with decreased rates of mortality and decreased rates …

Head and neck cancer is a malignant tumour with a high mortality rate characterized by late
diagnosis, high recurrence and metastasis rates, and poor prognosis. Head and neck …

Summary NRF2 (nuclear factor erythroid 2-related factor 2) is a master regulator of
protective responses in healthy tissues. However, when it is active in tumor cells, it can result …

Abstract Purpose: Cisplatin (CDDP)-based chemotherapy is a first-line treatment for patients
with advanced head and neck squamous cell carcinomas (HNSCC), despite a high rate of …

Many types of human cancers suppress the expression of argininosuccinate synthase 1
(ASS1), a rate-limiting enzyme for arginine production. Although dependency on exogenous …

Cancer is a challenging to treat disease with a high mortality rate worldwide, nevertheless
advances in science has led to a decrease in the number of death cases caused by cancer …

Cancer stem cells (CSCs) are a small population of tumor cells characterized by self-
renewal and differentiation capacity. CSCs are currently postulated as the driving force that …

Immunogenic cell death (ICD) has gained increasing attention due to its capacity to trigger
anticancer immunity. Herein, we report a series of fabricated cationic spherical polypeptides …

Higher body fat content is related to a higher risk of mortality, and obesity-related cancer
represents approximately 40% of all cancer patients diagnosed each year. Furthermore …

Immunotherapy has revolutionized cancer treatment, yet the efficacy of immunotherapeutic
approaches remains limited. Resistance to ferroptosis is one of the reasons for the poor …