Transposable elements shape the evolution of mammalian development

AD Senft, TS Macfarlan - Nature Reviews Genetics, 2021 - nature.com
Transposable elements (TEs) promote genetic innovation but also threaten genome stability.
Despite multiple layers of host defence, TEs actively shape mammalian-specific …

Ten things you should know about transposable elements

G Bourque, KH Burns, M Gehring, V Gorbunova… - Genome biology, 2018 - Springer
Transposable elements (TEs) are major components of eukaryotic genomes. However, the
extent of their impact on genome evolution, function, and disease remain a matter of intense …

Systematic evaluation of horizontal gene transfer between eukaryotes and viruses

NAT Irwin, AA Pittis, TA Richards, PJ Keeling - Nature microbiology, 2022 - nature.com
Gene exchange between viruses and their hosts acts as a key facilitator of horizontal gene
transfer and is hypothesized to be a major driver of evolutionary change. Our understanding …

Transposable elements in human genetic disease

LM Payer, KH Burns - Nature Reviews Genetics, 2019 - nature.com
Transposable elements are abundant in the human genome, and great strides have been
made in pinpointing variations in these repetitive sequences using whole-genome …

Origins and evolutionary consequences of ancient endogenous retroviruses

WE Johnson - Nature Reviews Microbiology, 2019 - nature.com
Retroviruses infect a broad range of vertebrate hosts that includes amphibians, reptiles, fish,
birds and mammals. In addition, a typical vertebrate genome contains thousands of loci …

[HTML][HTML] The role of epigenetics in placental development and the etiology of preeclampsia

C Apicella, CSM Ruano, C Méhats, F Miralles… - International journal of …, 2019 - mdpi.com
In this review, we comprehensively present the function of epigenetic regulations in normal
placental development as well as in a prominent disease of placental origin, preeclampsia …

The arms race between KRAB–zinc finger proteins and endogenous retroelements and its impact on mammals

M Bruno, M Mahgoub… - Annual Review of …, 2019 - annualreviews.org
Nearly half of the human genome consists of endogenous retroelements (EREs) and their
genetic remnants, a small fraction of which carry the potential to propagate in the host …

Virus–host coevolution with a focus on animal and human DNA viruses

GL Kaján, A Doszpoly, ZL Tarján, MZ Vidovszky… - Journal of molecular …, 2020 - Springer
Viruses have been infecting their host cells since the dawn of life, and this extremely long-
term coevolution gave rise to some surprising consequences for the entire tree of life. It is …

[HTML][HTML] The placenta goes viral: Retroviruses control gene expression in pregnancy

EB Chuong - PLoS biology, 2018 - journals.plos.org
The co-option of endogenous retroviruses (ERVs) is increasingly recognized as a recurrent
theme in placental biology, which has far-reaching implications for our understanding of …

The diverse evolutionary histories of domesticated metaviral capsid genes in mammals

WS Henriques, JM Young, A Nemudryi… - Molecular Biology …, 2024 - academic.oup.com
Selfish genetic elements comprise significant fractions of mammalian genomes. In rare
instances, host genomes domesticate segments of these elements for function. Using a …