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Transposable elements shape the evolution of mammalian development
AD Senft, TS Macfarlan - Nature Reviews Genetics, 2021 - nature.com
Transposable elements (TEs) promote genetic innovation but also threaten genome stability.
Despite multiple layers of host defence, TEs actively shape mammalian-specific …
Despite multiple layers of host defence, TEs actively shape mammalian-specific …
Ten things you should know about transposable elements
Transposable elements (TEs) are major components of eukaryotic genomes. However, the
extent of their impact on genome evolution, function, and disease remain a matter of intense …
extent of their impact on genome evolution, function, and disease remain a matter of intense …
Systematic evaluation of horizontal gene transfer between eukaryotes and viruses
Gene exchange between viruses and their hosts acts as a key facilitator of horizontal gene
transfer and is hypothesized to be a major driver of evolutionary change. Our understanding …
transfer and is hypothesized to be a major driver of evolutionary change. Our understanding …
Transposable elements in human genetic disease
LM Payer, KH Burns - Nature Reviews Genetics, 2019 - nature.com
Transposable elements are abundant in the human genome, and great strides have been
made in pinpointing variations in these repetitive sequences using whole-genome …
made in pinpointing variations in these repetitive sequences using whole-genome …
Origins and evolutionary consequences of ancient endogenous retroviruses
WE Johnson - Nature Reviews Microbiology, 2019 - nature.com
Retroviruses infect a broad range of vertebrate hosts that includes amphibians, reptiles, fish,
birds and mammals. In addition, a typical vertebrate genome contains thousands of loci …
birds and mammals. In addition, a typical vertebrate genome contains thousands of loci …
[HTML][HTML] The role of epigenetics in placental development and the etiology of preeclampsia
C Apicella, CSM Ruano, C Méhats, F Miralles… - International journal of …, 2019 - mdpi.com
In this review, we comprehensively present the function of epigenetic regulations in normal
placental development as well as in a prominent disease of placental origin, preeclampsia …
placental development as well as in a prominent disease of placental origin, preeclampsia …
The arms race between KRAB–zinc finger proteins and endogenous retroelements and its impact on mammals
M Bruno, M Mahgoub… - Annual Review of …, 2019 - annualreviews.org
Nearly half of the human genome consists of endogenous retroelements (EREs) and their
genetic remnants, a small fraction of which carry the potential to propagate in the host …
genetic remnants, a small fraction of which carry the potential to propagate in the host …
Virus–host coevolution with a focus on animal and human DNA viruses
Viruses have been infecting their host cells since the dawn of life, and this extremely long-
term coevolution gave rise to some surprising consequences for the entire tree of life. It is …
term coevolution gave rise to some surprising consequences for the entire tree of life. It is …
[HTML][HTML] The placenta goes viral: Retroviruses control gene expression in pregnancy
EB Chuong - PLoS biology, 2018 - journals.plos.org
The co-option of endogenous retroviruses (ERVs) is increasingly recognized as a recurrent
theme in placental biology, which has far-reaching implications for our understanding of …
theme in placental biology, which has far-reaching implications for our understanding of …
The diverse evolutionary histories of domesticated metaviral capsid genes in mammals
Selfish genetic elements comprise significant fractions of mammalian genomes. In rare
instances, host genomes domesticate segments of these elements for function. Using a …
instances, host genomes domesticate segments of these elements for function. Using a …