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Benzodiazepines in the management of seizures and status epilepticus: a review of routes of delivery, pharmacokinetics, efficacy, and tolerability
R Kienitz, L Kay, I Beuchat, S Gelhard… - CNS drugs, 2022 - Springer
Status epilepticus (SE) is an acute, life-threatening medical condition that requires
immediate, effective therapy. Therefore, the acute care of prolonged seizures and SE is a …
immediate, effective therapy. Therefore, the acute care of prolonged seizures and SE is a …
Why won't it stop? The dynamics of benzodiazepine resistance in status epilepticus
Status epilepticus is a life-threatening neurological emergency that affects both adults and
children. Approximately 36% of episodes of status epilepticus do not respond to the current …
children. Approximately 36% of episodes of status epilepticus do not respond to the current …
International consensus recommendations for management of new onset refractory status epilepticus including febrile infection‐related epilepsy syndrome …
Objective This study was undertaken to develop consensus‐based recommendations for the
management of adult and pediatric patients with new onset refractory status epilepticus …
management of adult and pediatric patients with new onset refractory status epilepticus …
Therapeutic strategies to ameliorate neuronal damage in epilepsy by regulating oxidative stress, mitochondrial dysfunction, and neuroinflammation
S Madireddy, S Madireddy - Brain sciences, 2023 - mdpi.com
Epilepsy is a central nervous system disorder involving spontaneous and recurring seizures
that affects 50 million individuals globally. Because approximately one-third of patients with …
that affects 50 million individuals globally. Because approximately one-third of patients with …
Management of status epilepticus, refractory status epilepticus, and super-refractory status epilepticus
E Trinka, M Leitinger - CONTINUUM: Lifelong Learning in …, 2022 - journals.lww.com
PURPOSE OF REVIEW Status epilepticus is a serious condition caused by disorders and
diseases that affect the central nervous system. In status epilepticus, hypersynchronous …
diseases that affect the central nervous system. In status epilepticus, hypersynchronous …
[HTML][HTML] Epilepsy disease and nose-to-brain delivery of polymeric nanoparticles: an overview
T Musumeci, A Bonaccorso, G Puglisi - Pharmaceutics, 2019 - mdpi.com
Epilepsy is the fourth most common global neurological problem, which can be considered a
spectrum disorder because of its various causes, seizure types, its ability to vary in severity …
spectrum disorder because of its various causes, seizure types, its ability to vary in severity …
Dogs as a natural animal model of epilepsy
W Löscher - Frontiers in veterinary science, 2022 - frontiersin.org
Epilepsy is a common neurological disease in both humans and domestic dogs, making
dogs an ideal translational model of epilepsy. In both species, epilepsy is a complex brain …
dogs an ideal translational model of epilepsy. In both species, epilepsy is a complex brain …
S (+)-ketamine: Current trends in emergency and intensive care medicine
H Trimmel, R Helbok, T Staudinger, W Jaksch… - Wiener klinische …, 2018 - Springer
Summary S (+)-ketamine, the pure dextrorotatory enantiomer of ketamine has been
available for clinical use in analgesia and anesthesia for more than 25 years. The main …
available for clinical use in analgesia and anesthesia for more than 25 years. The main …
[HTML][HTML] 25 years of advances in the definition, classification and treatment of status epilepticus
E Trinka, R Kälviäinen - Seizure, 2017 - Elsevier
Purpose Status epilepticus (SE) requires not only urgent symptomatic treatment with
antiepileptic drugs but also rapid identification and treatment of its cause. This narrative …
antiepileptic drugs but also rapid identification and treatment of its cause. This narrative …
Lacosamide in status epilepticus: systematic review of current evidence
Objective The intravenous formulation of lacosamide (LCM) and its good overall tolerability
and safety favor the use in status epilepticus (SE). The aim of this systematic review was to …
and safety favor the use in status epilepticus (SE). The aim of this systematic review was to …