Most research on mechanisms of aging is being conducted in a very limited number of
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …

Many of the> 2 million animal species that inhabit Earth have developed survival
mechanisms that aid in the prevention of obesity, kidney disease, starvation, dehydration …

The mitochondria of various tissues from mice, naked mole rats (NMRs), and bats possess
two mechanistically similar systems to prevent the generation of mitochondrial reactive …

Naked mole rats (NMRs) live an exceptionally long life, appear not to exhibit age-related
decline in physiological capacity and are resistant to age-related diseases. However, it has …

Humans are unique in their sophisticated culture and societal structures, their complex
languages, and their extensive tool use. According to the human self-domestication …

The self-domestication hypothesis suggests that, like mammalian domesticates, humans
have gone through a process of selection against aggression–a process that in the case of …

For a long time Nrf2 transcription factor has been attracting attention of researchers
investigating phenomenon of aging. Numerous studies have investigated effects of Nrf2 on …

Despite intensive research, no satisfactory therapeutic options have been found for aging
and age-related diseases. The British scientist Leslie Orgel stated that evolution is cleverer …

The subterranean-dwelling naked mole-rat (Heterocephalus glaber) is an extremophilic
rodent, able to thrive in the harsh underground conditions of sub-Saharan Northeast Africa …

Naked mole‐rats express many unusual traits for such a small rodent. Their morphology,
social behaviour, physiology, and ageing have been well studied over the past half‐century …