The extended granin family: structure, function, and biomedical implications

A Bartolomucci, R Possenti, SK Mahata… - Endocrine …, 2011 - academic.oup.com
The chromogranins (chromogranin A and chromogranin B), secretogranins (secretogranin II
and secretogranin III), and additional related proteins (7B2, NESP55, proSAAS, and VGF) …

Spatial and temporal activation of spinal glial cells: role of gliopathy in central neuropathic pain following spinal cord injury in rats

YS Gwak, J Kang, GC Unabia, CE Hulsebosch - Experimental neurology, 2012 - Elsevier
In the spinal cord, neuron and glial cells actively interact and contribute to neurofunction.
Surprisingly, both cell types have similar receptors, transporters and ion channels and also …

Proinflammatory cytokine synthesis in the injured mouse spinal cord: multiphasic expression pattern and identification of the cell types involved

I Pineau, S Lacroix - Journal of Comparative Neurology, 2007 - Wiley Online Library
We have studied the spatial and temporal distribution of six proinflammatory cytokines and
identified their cellular source in a clinically relevant model of spinal cord injury (SCI). Our …

Upregulation of sodium channel Nav1. 3 and functional involvement in neuronal hyperexcitability associated with central neuropathic pain after spinal cord injury

BC Hains, JP Klein, CY Saab, MJ Craner… - Journal of …, 2003 - Soc Neuroscience
Spinal cord injury (SCI) can result in hyperexcitability of dorsal horn neurons and central
neuropathic pain. We hypothesized that these phenomena are consequences, in part, of …

Spinal cord contusion models

W Young - Progress in brain research, 2002 - Elsevier
Publisher Summary This chapter outlines the history and practice of animal spinal cord
contusion models, with particular emphasis on the Multicenter Animal Spinal Cord Injury …

Inflammation, degeneration and regeneration in the injured spinal cord: insights from DNA microarrays

FM Bareyre, ME Schwab - Trends in neurosciences, 2003 - cell.com
GeneChip® microarrays have recently been introduced to the field of neurobiology to
identify and monitor the expression levels of thousands of genes simultaneously. This …

Cytokine and growth factor activation in vivo and in vitro after spinal cord injury

E Garcia, J Aguilar-Cevallos… - Mediators of …, 2016 - Wiley Online Library
Spinal cord injury results in a life‐disrupting series of deleterious interconnected
mechanisms encompassed by the primary and secondary injury. These events are mediated …

Conditioning injury-induced spinal axon regeneration fails in interleukin-6 knock-out mice

WBJ Cafferty, NJ Gardiner, P Das, J Qiu… - Journal of …, 2004 - Soc Neuroscience
Regeneration of injured adult sensory neurons within the CNS is essentially abortive,
attributable in part to lesion-induced or revealed inhibitors such as the chondroitin sulfate …

JAK2 and STAT3 activation contributes to neuronal damage following transient focal cerebral ischemia

I Satriotomo, KK Bowen… - Journal of …, 2006 - Wiley Online Library
Increased levels of interleukin‐6 (IL‐6) play a role in post‐ischemic cerebral inflammation. IL‐
6 binding to its receptors induces phosphorylation of the receptor associated janus kinases …

Reaching training in rats with spinal cord injury promotes plasticity and task specific recovery

J Girgis, D Merrett, S Kirkland, GAS Metz, V Verge… - Brain, 2007 - academic.oup.com
In the current study we examined the effects of training in adult rats with a cervical spinal
cord injury (SCI). One group of rats received 6 weeks of training in a single pellet reaching …